DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and Etv6

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	XP_038963620.1	Gene:	Etv6 / 312777	RGDID:	1559537	Length:	464	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	89/368 - (24%)
Similarity:	141/368 - (38%)	Gaps:	92/368 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   527 HTGTFLHPN----LYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTS 587
            |.|..:|..    |:||:..:   |...|:                         |:||.  .:.
  Rat   146 HPGNSIHTKPEVLLHQNHEED---NCVQRT-------------------------PRTPA--ESL 180

  Fly   588 YFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQ 652
            :.|.||.......:...|.|...|...:||:..:|......::|:..:  ..|...|.|:.:||:
  Rat   181 HHNPPTIELLHRPRSPITTNHRPSPDPEQQRPLRSPLDNMIRRLSPAE--RAQGPRLQQENNHQE 243

  Fly   653 Q---QQQQQQQQH-PHSQLNGPHPHSHPHSH----------PHSHPHAGQHTHSTIAAAAAAAAA 703
            .   .....:..| |.|..:.|.| |.|...          |..||......||
  Rat   244 SYPLSVSPMENNHCPPSSESNPKP-SSPWQESTRVIQLMPSPIMHPLILNPRHS----------- 296

  Fly   704 SVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKP 768
              |....|.::...|....                  :|...|...||:||..:    ......|
  Rat   297 --VDFKQSRISEDGMHREG------------------KPINLSHREDLAYMNHI----MVSVSPP 337

  Fly   769 RKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHK 833
            .:..:.:|     |......||:::.:||.|..| ..||:|.::|..:|::||...::||||.||
  Rat   338 EEHAMPIG-----RIADCRLLWDYVYQLLSDSRY-ENFIRWEDKESKIFRIVDPNGLARLWGNHK 396

  Fly   834 NKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDII 876
            |:.:|.||.|.||||:||:..|:.|..||||:::|:..|.:|:
  Rat   397 NRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIM 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	36/79 (46%)
Etv6	XP_038963620.1	SAM_PNT-Tel_Yan	67..134	CDD:176085
Etv6	XP_038963620.1	ETS	350..436	CDD:197710	37/86 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3804
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810