DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and Etv5

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	XP_038944216.1	Gene:	Etv5 / 303828	RGDID:	1309590	Length:	528	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	100/397 - (25%)
Similarity:	139/397 - (35%)	Gaps:	116/397 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   558 NYYGSSGAGSGGTQP-GGPGNPQTPGYLTTSYFNAP--TAATAAASQRGTTINGY------HSLH 613
            ||.........|.:| ..|..|.:|.: ..|.|..|  |..|:|.:.....:.|.      |||.
  Rat   137 NYCAYDRKPPSGFKPLTPPATPLSPTH-QNSLFPPPQATLPTSALAPGAGPVQGVGPAPTPHSLP 200

  Fly   614 QQQQQQQ-------QSQQSQQQQQLAHQQLSHQQQQALHQQLSH-------------QQQQQQQQ 658
            :...|||       ..|..|..:.:...|  :..:|...:|||.             ..:...|:
  Rat   201 EPGSQQQTFAVPRPPHQPLQMPKMMPESQ--YPSEQRFQRQLSEPCRPFPPQSGVPGDTRPSYQR 263

  Fly   659 QQQHP-----HSQLNGPHPHSHPHSHPHSHP-------HAGQHTHSTIAAAAAAAAASVVSSSSS 711
            |...|     ...|.|.....|...:.|..|       |..|.............|.|.|.:..|
  Rat   264 QMSEPVVPAAPPPLQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYCADSEVPNCQS 328

  Fly   712 AVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPR------- 769
            ........|::..                                  ||...  |.||
  Rat   329 PYMRGRYFSSNHE----------------------------------GFTYE--KDPRLYFDDTC 357

  Fly   770 --KPKLEMGVKRRS---REG------STTYLWEFLLKLLQDREYCPRFIKWTNREKGV-FKLVDS 822
              ..:||..||:..   |||      .:..||:||:.||.|.... .||.||.|  |: |||::.
  Rat   358 VVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANA-HFIAWTGR--GMEFKLIEP 419

  Fly   823 KAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDII----------- 876
            :.|:|.||:.||:|.|||:.:.|:|||||::||:.||.|:|.||:||..|..:.
  Rat   420 EEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPF 484

  Fly   877 ---EIDC 880
               |.||
  Rat   485 LKAESDC 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	40/80 (50%)
Etv5	XP_038944216.1	ETS_PEA3_N	2..384	CDD:398352	54/285 (19%)
Etv5	XP_038944216.1	ETS	385..470	CDD:197710	42/87 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910