DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and FLI1

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_002008.2	Gene:	FLI1 / 2313	HGNCID:	3749	Length:	452	Species:	Homo sapiens

Alignment Length:	123	Identity:	50/123 - (40%)
Similarity:	66/123 - (53%)	Gaps:	17/123 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   757 LGGFQQRKAKKPRKPK------LEMGVKRRSREGS-TTYLWEFLLKLLQD--REYCPRFIKW--T 810
            |||.|.......::|:      |.....|.:..|| ...||:|||:||.|  ...|   |.|  |
Human   244 LGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASC---ITWEGT 305

  Fly   811 NREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQF 868
            |   |.||:.|...|:|.||..|:||:|||:.:.|||||||.:.|:.||.|:|..|:|
Human   306 N---GEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	41/84 (49%)
FLI1	NP_002008.2	SAM_PNT-FLI-1	114..204	CDD:188883
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..271		6/26 (23%)
		ETS	280..363	CDD:197710	41/87 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	433..452
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910