Protein Alignment Eip74EF and ETV4

DIOPT Version :9

• Sequence 1: NP_001014590.1
• Gene: Eip74EF / 39962
• FlyBaseID: FBgn0000567
• Length: 883
• Species: Drosophila melanogaster
• Sequence 2: NP_001073143.1
• Gene: ETV4 / 2118
• HGNCID: 3493
• Length: 484
• Species: Homo sapiens
• Alignment Length: 511
• Identity: 118/511 - (23%)
• Similarity: 181/511 - (35%)
• Gaps: 159/511 - (31%)

  Fly   435 QQQPLAI----PQRPLLHNLLSG--GAIHNPHHRNYTTATTGSFPPSPADSGVSDVDS-----SS 488
            ||.|...    |....|...|.|  |.:.:|          ||.||..::....|:..     .:
Human    12 QQVPYTFSSKSPGNGSLREALIGPLGKLMDP----------GSLPPLDSEDLFQDLSHFQETWLA 66

  Fly   489 SGGQPCADEL---------------KARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQ 538
            ....|.:||.               ..|:...|.:..:..|.:.:......:.|....|:.:.|.
Human    67 EAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSAYD 131

  Fly   539 NNAANSLRNIWNRSVGVPDNYYGSSGAG---------------SGGTQPGGPGNPQTPGYL--TT 586
            .          .|.:.:.....|:.|..               |.||....||:    |||  .:
Human   132 P----------PRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGH----GYLGEHS 182

  Fly   587 SYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQ---QALHQQL 648
            |.|..|             ::..||. ..|...::...:..|.||:.....:.||   |..|..|
Human   183 SVFQQP-------------LDICHSF-TSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPL 233

  Fly   649 SHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAV 713
            ..|..|....|     ..:||           |.:|.||                .|:....:..
Human   234 YEQAGQPAVDQ-----GGVNG-----------HRYPGAG----------------VVIKQEQTDF 266

  Fly   714 AAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKP------- 771
            |..:.::..|:........:|.|     |...::.|         |::     ||.:|
Human   267 AYDSDVTGCASMYLHTEGFSGPS-----PGDGAMGY---------GYE-----KPLRPFPDDVCV 312

  Fly   772 ---KLEMGVKRRS----REG------STTYLWEFLLKLLQDREYCPRFIKWTNREKGV-FKLVDS 822
               |.|..:|:..    |||      ....||:||:.||.|.... .||.||.|  |: |||::.
Human   313 VPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNA-HFIAWTGR--GMEFKLIEP 374

  Fly   823 KAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEI 878
            :.|:||||:.||:|.|||:.:.|:|||||::||:.||.|:|.||:||..|:.:..:
Human   375 EEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFSL 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	41/80 (51%)
ETV4	NP_001073143.1	ETS_PEA3_N	8..339	CDD:309665	74/415 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..115		3/24 (13%)
		ETS	341..424	CDD:197710	43/85 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910