Protein Alignment Eip74EF and ELF4

DIOPT Version :10

• Sequence 1: NP_730288.1
• Gene: Eip74EF / 39962
• FlyBaseID: FBgn0000567
• Length: 883
• Species: Drosophila melanogaster
• Sequence 2: NP_001412.1
• Gene: ELF4 / 2000
• HGNCID: 3319
• Length: 663
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 99/221 - (44%)
• Similarity: 123/221 - (55%)
• Gaps: 33/221 - (14%)

  Fly   686 AGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPAT------ 744
            |..||.||........:.|.:.......:.:.||..|..|.|...      .:.:.||:
Human    87 ATSHTMSTAEVLLNMESPSDILDEKQIFSTSEMLPDSDPAPAVTL------PNYLFPASEPDALN 145

  Fly   745 --SSVSYDLSYMLELGGFQQRKAKKPRK-------------------PKLEMGVKRRSREGSTTY 788
              ...|....:.||....::..|||..|                   |.:.:..|.:..:|||.|
Human   146 RAGDTSDQEGHSLEEKASREESAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIY 210

  Fly   789 LWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQR 853
            ||||||.|||||..||::||||.||||:||||||||||:|||..|||||||||||||||||||||
Human   211 LWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQR 275

  Fly   854 GILAKVDGQRLVYQFVDVPKDIIEID 879
            ||||||:||||||||.::|||::.|:
Human   276 GILAKVEGQRLVYQFKEMPKDLVVIE 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_730288.1	ETS	786..872	CDD:197710	71/85 (84%)
ELF4	NP_001412.1	Elf-1_N	2..104	CDD:463529	5/16 (31%)
		RUNX1-binding. /evidence=ECO:0000269|PubMed:10207087	87..206		22/124 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..203		9/62 (15%)
		ETS	208..290	CDD:197710	69/81 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	302..353		99/221 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	493..518
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..605
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	635..663