DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Eip74EF and Elf1

DIOPT Version :9

Sequence 1:NP_001014590.1 Gene:Eip74EF / 39962 FlyBaseID:FBgn0000567 Length:883 Species:Drosophila melanogaster
Sequence 2:NP_001273340.1 Gene:Elf1 / 13709 MGIID:107180 Length:612 Species:Mus musculus


Alignment Length:222 Identity:106/222 - (47%)
Similarity:132/222 - (59%) Gaps:38/222 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   685 HAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATS-SVS 748
            |.|..|..||.||.|...   :.|.|..|.....::.:..:::        ...::.|.|. ||:
Mouse    90 HNGDETIETIEAAEALLN---IDSPSPPVLDEKQINNNIFSSS--------EDDIVAPITHVSVT 143

  Fly   749 YD-LSYMLELGGFQ-------------QRKAKKPRK------------PKLEMGVKRRSREGSTT 787
            .| :..::|....|             |||.||.||            |.:.:..|.:..:|:|.
Mouse   144 LDGIPEVMETQQVQETNADSPGASSPEQRKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTI 208

  Fly   788 YLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQ 852
            |||||||.||||:..||::||||.||||:||||||||||||||.|||||||||||||||||||||
Mouse   209 YLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQ 273

  Fly   853 RGILAKVDGQRLVYQFVDVPKDIIEID 879
            |||||||:||||||||.::|||:|.||
Mouse   274 RGILAKVEGQRLVYQFKEMPKDLIYID 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Eip74EFNP_001014590.1 Ets 789..869 CDD:278602 69/79 (87%)
Elf1NP_001273340.1 Elf-1_N 2..111 CDD:372034 8/23 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 156..199 9/42 (21%)
ETS 207..289 CDD:197710 70/81 (86%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 300..361 1/1 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 562..586
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 155 1.000 Domainoid score I4218
eggNOG 1 0.900 - - E1_KOG3804
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42817
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR11849
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
65.960

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