DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Eip74EF and gabpa

DIOPT Version :9

Sequence 1:	NP_001014590.1	Gene:	Eip74EF / 39962	FlyBaseID:	FBgn0000567	Length:	883	Species:	Drosophila melanogaster
Sequence 2:	NP_001116494.1	Gene:	gabpa / 100126064	XenbaseID:	XB-GENE-987250	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	145	Identity:	55/145 - (37%)
Similarity:	79/145 - (54%)	Gaps:	21/145 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   740 IQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTT------YLWEFLLKLLQ 798
            |||...:.       :::...|.:.||..|.|::  ..:.||..|:.|      .||:|||:||.
Frog   277 IQPTAQTT-------IKVINSQTKVAKIQRTPRI--SGEDRSSPGNRTGNNGQIQLWQFLLELLT 332

  Fly   799 DREY--CPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDG 861
            |::.  |   |.|.. ::|.|||...:.|::.||..||||.||||.:.|||||||...::.||.|
Frog   333 DKDARDC---ISWVG-DEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKVQG 393

  Fly   862 QRLVYQFVDVPKDII 876
            :|.||:||...|.:|
Frog   394 KRFVYKFVCDLKTLI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Eip74EF	NP_001014590.1	Ets	789..869	CDD:278602	39/81 (48%)
gabpa	NP_001116494.1	GABP-alpha	40..119	CDD:371630
		SAM_PNT-GABP-alpha	168..254	CDD:176084
		ETS	320..404	CDD:197710	41/87 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910