Protein Alignment CycT and CCNC

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_005181.2
• Gene: CCNC / 892
• HGNCID: 1581
• Length: 283
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 68/267 - (25%)
• Similarity: 116/267 - (43%)
• Gaps: 51/267 - (19%)

  Fly    45 WYFSNDQLANSPSRRCGIKGDDELQYRQMTAY---LIQEMGQRLQVSQLCINTAIVYMHRFYAFH 106
            |......|..  .|:..:|...|.:|.::..:   :||.:|:.|::.|..|.||.||..||||.:
Human    14 WILDKQDLLK--ERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARY 76

  Fly   107 SFTHFHRNSMASASLFLAAKVEE-----QPRKLEHVIRAANKCLPPTTEQNYAELAQELVFNEN- 165
            |........||...:|||:||||     ..|    :|.||...|  .|..:|| ..:|..:..|
Human    77 SLKSIDPVLMAPTCVFLASKVEEFGVVSNTR----LIAAATSVL--KTRFSYA-FPKEFPYRMNH 134

  Fly   166 ------VLLQTLGFDVAIDHPHTHVVRTCQLVKACKDLAQTSYFL-----ASNSLHLTSMCLQYR 219
                  .||:.:...:.:.||:.      .|::..:|:.|....|     ..|..:.|.:||.|.
Human   135 ILECEFYLLELMDCCLIVYHPYR------PLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYP 193

  Fly   220 PTVVACFCIYLACKWSRWEIPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYE--------KSP 276
            |.::|..|:::||      :.|..:.:.||  .:.:|.::.:.::....:.:||        |..
Human   194 PFMIALACLHVAC------VVQQKDARQWF--AELSVDMEKILEIIRVILKLYEQWKNFDERKEM 250

  Fly   277 ARLKSKL 283
            |.:.||:
Human   251 ATILSKM 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	42/143 (29%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	20/93 (22%)
CCNC	NP_005181.2	CYCLIN_CCNC_rpt1	40..146	CDD:410217	36/112 (32%)
		CYCLIN_CCNC_rpt2	154..245	CDD:410218	22/104 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..283		2/6 (33%)