Protein Alignment CycT and Ccnl2

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: XP_036020147.1
• Gene: Ccnl2 / 56036
• MGIID: 1927119
• Length: 519
• Species: Mus musculus
• Alignment Length: 527
• Identity: 142/527 - (26%)
• Similarity: 214/527 - (40%)
• Gaps: 113/527 - (21%)

  Fly     8 MPQAATASSSSSASAAASA----------SGIPITANNNLPFEKDKIWYFSNDQLANSPSRRCGI 62
            |..|:.|.||.||.||..:          ||:.||..|.|         ..:|:|..:||...|:
Mouse    12 MAPASAACSSGSAGAAPGSQGVLIGDRLYSGVLITLENCL---------LPDDKLRFTPSMSSGL 67

  Fly    63 KGDDELQYRQMTAYLIQEMGQRLQVSQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKV 127
            ..|.|...|.:...|||..|..|::.|:.:.|..|...||:...||.......::.|.:.||:|:
Mouse    68 DVDTETGLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKI 132

  Fly   128 EEQPRKLEHVI---------RAANKCLPPTTEQNYAELAQELVFNENVLLQTLGFDVAIDHPHTH 183
            ||.||::..||         |...|.:|...:|.|..|..:::..|..:|:.|||.|.:.|||..
Mouse   133 EEAPRRIRDVINVFHRLRHLREKKKPVPLVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKI 197

  Fly   184 VVRTCQLVKACKD--LAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQSTEGK 246
            :|...|:::..::  |.||::...::||. |.:.::::|..:||.|||||.:  ..|||.... .
Mouse   198 IVMYLQVLECERNQHLVQTAWNYMNDSLR-TDVFVRFQPESIACACIYLAAR--TLEIPLPNR-P 258

  Fly   247 HWFYYVDKTVSLDLLKQLTDEFIAIY----------EKSPARLKSKLNSIKAIAQGASNRTANSK 301
            |||.....|.  :.::::..:.:.:|          |....:.|..:...||.|:|....||...
Mouse   259 HWFLLFGATE--EEIQEICFKILQLYTRKKVDLTHLESEVEKRKHAIEEAKARAKGLLPGTAPGL 321

  Fly   302 D-----KPKEDWKITEMMKGYHSNITTPPE----------------------LLNGNDSRDRDRD 339
            |     .|..  |:.|..|.......:||.                      ||.|.:||.:.|.
Mouse   322 DSAAGFSPAP--KLVESPKEGKGGKPSPPSGKSAKRKMEGPKKAQGHSPVNGLLKGQESRSQSRS 384

  Fly   340 RERERERERDPSSLLPPPAMVPQQRRQDGGHQRSSSVSGVPGSSSSSSSSS---------HKMPN 395
            ||:...|.       |..:..|::|:.|.|     |.||  ||.|.|.|.|         |:...
Mouse   385 REQSYSRS-------PSRSASPKRRKSDSG-----STSG--GSKSQSRSRSRSDSPPRQVHRGAP 435

  Fly   396 YPGGMPPDAHTDHKSKQPGYNNRMP-SSHQRSSSSGLGSSGSGSQRSSSSSSSSSQQPGRPSMPV 459
            |.|.   :.....|||...|..:.| .|..||||           ||.|.|...:...|:.....
Mouse   436 YKGS---EVRGSRKSKDCKYLTQKPHKSRSRSSS-----------RSRSRSRERTDNSGKYKKKS 486

  Fly   460 DYHKSSR 466
            .|::..|
Mouse   487 HYYRDQR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	40/137 (29%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	26/90 (29%)
Ccnl2	XP_036020147.1	CYCLIN_CCNL2_rpt1	33..188	CDD:410293	46/163 (28%)
		CYCLIN_CCNL2_rpt2	193..315	CDD:410296	33/127 (26%)