Protein Alignment CycT and Ccnk

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_001103142.1
• Gene: Ccnk / 500715
• RGDID: 1595690
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 720
• Identity: 165/720 - (22%)
• Similarity: 267/720 - (37%)
• Gaps: 211/720 - (29%)

  Fly    30 PITANNNLPFEKDKIWYFSNDQLANSPSRRCGIKGDDELQYRQMTAYLIQEMGQRLQVSQLCINT 94
            |...:.||...| ..||:....||::||:..|:....|.:||:..|..|.::|.||.:....:.|
  Rat    10 PSVTSANLDHTK-PCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLAT 73

  Fly    95 AIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPPTTEQNYAELA-- 157
            .|:|.||||.||||..|.|....:..||||.||||.|:|.:.:|:.|...|   .:..:.:..
  Rat    74 GIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLL---NDVQFGQFGDD 135

  Fly   158 --QELVFNENVLLQTLGFDVAIDHPHTHVVRTCQLVKACKD----LAQTSYFLASNSLHLTSMCL 216
              :|::..|.:||||:.||:.::||:..:::..:.:|..|:    |.|.::...::|| .|::.|
  Rat   136 PKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSL-CTTLSL 199

  Fly   217 QYRPTVVACFCIYLACKWSRWEIPQSTEG---KHWFYYVDKTVSLDLLKQLTDEFIAIY----EK 274
            |:.|.::|...:|||.:..::||.:.|..   :.|:....:.|.:|:|:.:..:.:.:|    ::
  Rat   200 QWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQ 264

  Fly   275 SPARLKSKLNSIKAI--------------AQGASNRTANSKDKPKEDWKITEMMKGYHSNITTPP 325
            .|.....:|....::              :||:.......||..::..:..:..:........|.
  Rat   265 MPHHTPHQLQQPPSLQPTPQVPPVPQAQPSQGSEAAQPQQKDAQQQQQQQQQQQQQQQQQAQQPK 329

  Fly   326 ELLNGNDSRDRDRDRERER-----ERERDPSSLLPPPAMVPQQRRQDGGHQRSSSVSGVPGSSSS 385
            :     .|......|:.:|     .:|.:.::..|||..:|   :.:..|         |....:
  Rat   330 K-----PSPQPSPPRQAKRAVVVSPKEENKATEPPPPPKIP---KLEAAH---------PPLPPA 377

  Fly   386 SSSSSHKMPNYPG------------------GMPPDAHTDHKSKQPGYNNRMPSSHQRSSSSGLG 432
            ......|:|..|.                  .:||.||.....:.|...:|.|.....|..:|:.
  Rat   378 HPPPDRKLPLAPALGEAEPTGPVETSDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMS 442

  Fly   433 S-----SGSGSQRSSSSSSSSSQQPGRPSMPVDYHKSSRGMPPVGVGMPPHGSHKMTSGSKPQQP 492
            :     ||.|.|  |..|...::.|...::|..|.      ||..:...||        ..|..|
  Rat   443 TTSSYMSGEGYQ--SLQSMMKTEGPSYGALPPAYG------PPAHLTYHPH--------VYPPNP 491

  Fly   493 QQQPVPHPSASNSSASGMSSKDKSQSNKMYPNAPPPYSNSAPQNPLMSRGGYPGASNGSQPPPPA 557
            ...|||.|.||                     .|||  ...|..|     |||       ||||.
  Rat   492 PPPPVPPPPAS---------------------FPPP--TIPPPTP-----GYP-------PPPPT 521

  Fly   558 GYGGHRSKSGSTVHGMPPFEQQLPYSQSQSYGHMQQQPVPQSQQQQMPPEASQHSLQSKNSLFSP 622
             |..:          .||...:||.:.:                  :||
  Rat   522 -YNPN----------FPPPPPRLPPTHA------------------VPP---------------- 541

  Fly   623 EWPDIKKEPMSQSQPQPFNGL----LPPPA-PPGHDYKLNSHPRDKESPKKERLTPTKKDKHRPV 682
                         .|.|..||    .|||| |||           .:.|....:.|       |.
  Rat   542 -------------HPPPGLGLPPASYPPPAVPPG-----------GQPPVPPPIPP-------PG 575

  Fly   683 MPPVG 687
            |||||
  Rat   576 MPPVG 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	47/132 (36%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	23/95 (24%)
Ccnk	NP_001103142.1	CYCLIN_CCNK_rpt1	40..154	CDD:410233	41/116 (35%)
		CYCLIN_CCNK_rpt2	158..258	CDD:410234	23/100 (23%)