Protein Alignment CycT and Ccnt2

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_001100641.1
• Gene: Ccnt2 / 304758
• RGDID: 1309205
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 812
• Identity: 274/812 - (33%)
• Similarity: 382/812 - (47%)
• Gaps: 170/812 - (20%)

  Fly    45 WYFSNDQLANSPSRRCGIKGDDELQYRQMTAYLIQEMGQRLQVSQLCINTAIVYMHRFYAFHSFT 109
            |:|:.:||.|:||||||::.|:||.:||..|.|||:|||||.||||.||||||||||||..||||
  Rat    11 WFFTREQLENTPSRRCGVEADEELSHRQQAANLIQDMGQRLNVSQLTINTAIVYMHRFYMHHSFT 75

  Fly   110 HFHRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPP------TTEQNYAELAQELVFNENVLL 168
            .|:||.::..:||||||||||.|||||||:.|:.||.|      |....|.:..||||..|.::|
  Rat    76 KFNRNIISPTALFLAAKVEEQARKLEHVIKVAHACLHPLEPLLDTKCDAYLQQTQELVLLETIML 140

  Fly   169 QTLGFDVAIDHPHTHVVRTCQLVKACKDLAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACK 233
            |||||::.|:||||.||:..|||:|.|||||||||:|:||||||:.||||:|||:||.||:||||
  Rat   141 QTLGFEITIEHPHTDVVKCTQLVRASKDLAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLACK 205

  Fly   234 WSRWEIPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYEKSPARLKSKLNSIKAIAQGASNRTA 298
            ||.||||.||:||||:.|||.||:|:||.:||.||:.|.||:|:||| ::.:.:|:|:
  Rat   206 WSNWEIPVSTDGKHWWEYVDPTVTLELLDELTHEFLQILEKTPSRLK-RIRNWRAMAK------- 262

  Fly   299 NSKDKPKEDWKITEMMKGYHSNITTP---PELLNGNDSRDRDRDRERERERERDPSSLLPPP--- 357
                |||.|.:::|          ||   ..|:..:...|...........::..:|..|.|
  Rat   263 ----KPKVDGQVSE----------TPLLGSSLVQNSILVDSVTGVPANPSFQKPSTSTFPAPLPL 313

  Fly   358 ----AMVPQQRRQDGGHQRSSSVSGVPGSSSSSSSSSHKMPNYPGGMPPDAHTDHKSKQPGYNNR 418
                ..|...|..|.|    |.::|:| |||.:.||..:.|::    |..|.||     |.|..:
  Rat   314 TSGSTSVQDGRASDTG----SVLAGMP-SSSYTVSSHQEWPHH----PDSARTD-----PVYTQK 364

  Fly   419 MPSSHQRSSSSGLGSSGSGSQ----RSSSSSSSSSQQPGRPSMPVDYHKSSRGMPPVGVGMPPHG 479
            ..::.            ||||    :...|.:..|....||....|:..:.:.....|.....||
  Rat   365 QEATL------------SGSQYLSFQQGPSMALHSGLHHRPDKVADHSSAKQEYTHKGGSSKHHG 417

  Fly   480 SHKMTSGSKPQQPQQQPVPHPSASNSSASGMSSKDKSQSNKMYPNAPPPYSNSAPQNPLMSRGGY 544
            ....|.|..||:                   .|.||.:..:.....           .|.||..|
  Rat   418 PIPATPGVVPQK-------------------MSLDKYREKRKLETL-----------DLDSRDHY 452

  Fly   545 PGASNGSQPPPPAGYGGHRSKSGSTVHGMPPFEQQLPYSQS-QSYGHMQQQ-----------PVP 597
            ..|....|..    :|..::.:|::|  ..|.:.:||.:.| :...|:.::           |:|
  Rat   453 MAAHAEQQHK----HGPAQAVAGTSV--TSPIKMKLPLTNSDKPEKHLAEKRERSGSLKLRIPIP 511

  Fly   598 QSQQQQMPPE--ASQHSLQSKNSLFSPEWPDIKKEPMSQSQPQPFNGLLPPPAPPGHDYKLNSHP 660
                   ||:  .|:..|:.|..:.|.|......|...:|:..      .|.....|..|...||
  Rat   512 -------PPDKGPSKEELKMKIKVSSSERHSSSDEGSGKSKHS------SPHISRDHKEKHKEHP 563

  Fly   661 --RDKESPKKERLTPTKKDKHRPVMP------PVGSGNSSSGSGSSKPMLPPHKKQIPHGGDLLT 717
              |...|.|...:..:...||...||      |||.|.....||      |..:|:: |..|...
  Rat   564 ANRHHSSHKHLHMHSSGGSKHADGMPPTVLRSPVGLGPEGISSG------PSARKKL-HINDASH 621

  Fly   718 NPGESGSLKRPNEISGS--------QYGLNKLDEIDNSNMP-------------REKLRKLDTTT 761
            |  ....:.:.::.|||        || |:....:.|..:|             ...|.|||...
  Rat   622 N--HHSKMSKSSKSSGSSSSSSSVKQY-LSSHSSVFNHPLPPPPPVTYQVGYGHLSTLVKLDKKP 683

  Fly   762 GLPTYPNYEEKHTPLNMSNGIETTPDLVRSLL 793
            ..|..|....:::..:.....:.|.|::.|||
  Rat   684 VEPHGPEANHEYSTSSQHMDYKDTFDMLDSLL 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	81/134 (60%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	63/88 (72%)
Ccnt2	NP_001100641.1	CYCLIN_CCNT2_rpt1	8..146	CDD:410299	81/134 (60%)
		CYCLIN_CCNT2_rpt2	150..259	CDD:410301	72/109 (66%)