Protein Alignment CycT and cit-1.2

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_498745.1
• Gene: cit-1.2 / 176126
• WormBaseID: WBGene00000508
• Length: 555
• Species: Caenorhabditis elegans
• Alignment Length: 684
• Identity: 151/684 - (22%)
• Similarity: 262/684 - (38%)
• Gaps: 216/684 - (31%)

  Fly    50 DQLANSPSRRCGIKGDDELQYRQMTAYLIQEMGQRL---QVSQLCINTAIVYMHRFYAFHSFTHF 111
            |.||::||||.|:..::||..||.....|.::..:|   :........|....:||:..||....
 Worm    29 DMLADTPSRREGMTYEEELSKRQQGGVFIFDIAMQLTHGKGEHGLSGVAATLFNRFFNVHSLKRC 93

  Fly   112 HRNSMASASLFLAAKVEEQPRKLEHVIRAANKCLPP-----TTEQNYAELAQELVFNENVLLQTL 171
            ....:|:|.:|||.|.|:.|:||::|:....:...|     .:||::.:....:...|:|||:|:
 Worm    94 DFRDVAAACVFLAGKNEDAPKKLKYVVTQLWQFKYPHNKQFQSEQHFLDQCNVVTLIEDVLLKTI 158

  Fly   172 GFDVAIDHPHTHVVRTCQLVK----ACKDLAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLAC 232
            .||:.:|.||.:|::..:.|:    ..||:.:|:|::|::.|.:|...::|....:|..|:.:|.
 Worm   159 SFDINVDLPHQYVLKLMRDVEKGRNVYKDMVKTAYYMATDVLIITDWSVRYSCASIATACVNIAA 223

  Fly   233 KWSRWE----IPQSTEGKHWFYYVDKTVSLDLLKQLTDEFIAIYEKSPARLKSKLNSIKAIAQGA 293
            .:....    :|.....: |:...|::::.:.::.:|.||:.|:.::|   :..:.|:|.|
 Worm   224 FFHNINMDDIVPFELSDR-WYRLEDQSMTREEVEAMTKEFLDIFSRNP---QFHIGSLKKI---- 280

  Fly   294 SNRTANSKDKPKEDWKITEMMKGYHSNITTPPELLNGNDSRDRDRDRERERERERDPSSLLPPPA 358
                     .|....||..|.....|.:|.     :|:.|..:..|.|..:.|.:..|:....|:
 Worm   281 ---------DPLGKVKIVGMPPQVSSTVTP-----SGSSSNLKKIDLESYKGRPKPLSNSSDSPS 331

  Fly   359 MVP-----------------QQRRQDGGHQRSSSVSGVPGSSSSSSSSSHKMPNYPGGMPPDAHT 406
            ..|                 :||.::...|:      :..:....|||||.:.:
 Worm   332 TRPSFLPDVKNQKVVEQELMEQRMKEAAQQK------IHRNGHRPSSSSHPLHH----------- 379

  Fly   407 DHKSKQPGYNNRMPSSHQRSSSSGLGSSGSGSQRSSSSSSSSSQQPGRPSMPVDYHKSSRGMPPV 471
             |.:.....||   |:||..|||||  |....|:..:..|.|:::    ||..:...||:
 Worm   380 -HSTSSSASNN---SNHQNRSSSGL--SAHQHQKPYNEDSRSAKR----SMMYEETNSSK----- 429

  Fly   472 GVGMPPHGSHKMTSGSKPQQPQQQPVPHPSASNSSASGMSSKDKSQS-------------NKMYP 523
                .|...:||:              ..::|:::.:.|.:...||:             |:|..
 Worm   430 ----KPRIDYKMS--------------FVASSSTTIATMHNDHFSQTTHQQNISTYARGVNEMML 476

  Fly   524 N--APPPYSNSAPQNPLMSRGGYPGASNGSQPPPPAGYGGHRSKSGSTVHGMPPFEQQLPYSQSQ 586
            |  |||         ||||....|                      ||...|
 Worm   477 NQVAPP---------PLMSVSAQP----------------------STYQKM------------- 497

  Fly   587 SYGHMQQQPVPQSQQQQMPPEASQHSLQSKNSLFSPEWPDIKKEPMSQSQPQPFNGLLPPPAPPG 651
                        ..:.|..|..|:|::.|...: ||  ||....|:||.       |||||.||
 Worm   498 ------------CMEYQRNPADSRHTMSSTQQI-SP--PDEPSPPVSQI-------LLPPPPPP- 539

  Fly   652 HDYKLNSHPRDKESPKKERLTPTKKDKHRPVMPP 685
                                         |::||
 Worm   540 -----------------------------PILPP 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	38/131 (29%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	19/96 (20%)
cit-1.2	NP_498745.1	CYCLIN_SF	40..161	CDD:477360	31/120 (26%)
		CYCLIN_CCNT_rpt2	166..263	CDD:410242	20/97 (21%)