Protein Alignment CycT and cit-1.1

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_001370392.1
• Gene: cit-1.1 / 176125
• WormBaseID: WBGene00000507
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 116/454 - (25%)
• Similarity: 199/454 - (43%)
• Gaps: 74/454 - (16%)

  Fly    23 AASASGIPITANNNLPFEKDKIWYFSNDQLANSPSRRCGIKGDDELQYRQMTAYLIQEM------ 81
            :.|:.|....|:...|.:    |.|:.:::..:.|.:.|:..::||..|||.|..||||
 Worm     2 SVSSRGAASPAHRTAPTK----WLFTKEEMKKTASIQEGMSREEELASRQMAAAFIQEMIDGLNN 62

  Fly    82 --GQRLQVSQLCINTAIVYMHRFYAFHSFTHFHRNSMASASLFLAAKVEEQPRKLEHVI-----R 139
              ..::::....:..|..:|||||..|||..:....:.:|.:|||.|.:|.||||.|||     |
 Worm    63 VKDPKMKIGHTGLCVAHTHMHRFYYLHSFKKYDYRDVGAACVFLAGKSQECPRKLSHVISVWRER 127

  Fly   140 AANKCLPPTTEQNYAELAQELVFNENVLLQTLGFDVAIDHPHTHVVRTCQLV---KACKDLAQTS 201
            ...|.|  |||....|.||.:|..|:::|||:.||:.:..||.:|:...:.|   :..:.|...:
 Worm   128 KDRKQL--TTETARNEAAQIIVLLESMILQTIAFDLNVHLPHIYVLDIMKKVDKKEHYRPLTSCA 190

  Fly   202 YFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEIPQ-----STEGKHWFYYVDKTVSLDLL 261
            |:.|::.:.:|...|:|....::...|:|...::...|.:     ..|...|:...|:|::.:.|
 Worm   191 YYFATDVIAVTDWSLRYSAASMSIVIIHLMAAYANVRIERLFADFINEDSPWYAKFDETMTNEKL 255

  Fly   262 KQLTDEFIAIYEKS-PARLKSKLNSIKAIAQGASNRTANSKDKPKEDWKITEMMKGYH---SNIT 322
            :::..:|:..|..| .....||.| .:.......|......|:.::....:.|:  :|   |.:.
 Worm   256 REMEVDFLVTYRNSCQFHHASKFN-FREHRPMLENPDVRKLDRTRDARSHSPMV--HHVPDSTVN 317

  Fly   323 TPP-------ELLNGNDSRDRDRDRERERERERDPSSLLPPPAMVPQQRRQDGGHQRSSS----- 375
            ..|       ||.....:::|..:.|| |:||||               |..|....|:|
 Worm   318 VRPRAYVPRDELTVERLNKERGVEEER-RKRERD---------------RMAGKLDSSTSSEKRA 366

  Fly   376 -VSGVPGSSSSSSSSSH------KMP---NYPGGMPPDAHTDHKSKQPGYNNRMPSSHQRSSSS 429
             :..:..:..||||||:      .:|   |:|  .||...:.:..|.........::|..||.|
 Worm   367 RIDPLANNFVSSSSSSNGKLAPPPIPPQLNFP--PPPIVSSGYNHKNQINRKNHENNHTNSSVS 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	50/141 (35%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	18/96 (19%)
cit-1.1	NP_001370392.1	CYCLIN_SF	19..160	CDD:477360	50/146 (34%)
		CYCLIN_CCNT_rpt2	165..263	CDD:410242	18/97 (19%)