Protein Alignment CycT and Ccnl1

DIOPT Version :10

• Sequence 1: NP_524127.2
• Gene: CycT / 39961
• FlyBaseID: FBgn0025455
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_446114.1
• Gene: Ccnl1 / 114121
• RGDID: 620864
• Length: 527
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 151/611 - (24%)
• Similarity: 243/611 - (39%)
• Gaps: 145/611 - (23%)

  Fly     7 PMPQAATASSSSSA-SAAASASGIPITANN---------------NLPFEKDKIWYFSNDQLANS 55
            |...||.||:||:| ||..|:||...|...               :|..:...|   ..::|:.:
  Rat     7 PTSTAAAASASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSVI---PEERLSPT 68

  Fly    56 PSRRCGIKGDDELQYRQMTAYLIQEMGQRLQVSQLCINTAIVYMHRFYAFHSFTHFHRNSMASAS 120
            ||.:.|:....|...|.:...|||..|..|::.|:.:.|..|..|||:...||.......:|.|.
  Rat    69 PSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMAC 133

  Fly   121 LFLAAKVEEQPRKLEHVI---------RAANKCLPPTTEQNYAELAQELVFNENVLLQTLGFDVA 176
            :.||:|:||.||::..||         |......|...:|||.....:::..|..:|:.|||.|.
  Rat   134 INLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVH 198

  Fly   177 IDHPHTHVVRTCQLVKACKD--LAQTSYFLASNSLHLTSMCLQYRPTVVACFCIYLACKWSRWEI 239
            :.|||..:|...|:::..::  |.||::...::||. |::.::::|..:||.|||||.:  ..:|
  Rat   199 VKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLR-TNVFVRFQPETIACACIYLAAR--ALQI 260

  Fly   240 PQSTEGKHWF-------------------YYVDKTVSLDLL-KQLTDEFIAIYEKSPARLKSK-- 282
            |..|. .|||                   .|..|..:.:|| |::....:|:.|   |:||:|
  Rat   261 PLPTR-PHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQE---AKLKAKGL 321

  Fly   283 -LNSIKAIAQGASNRTANSKDKPKEDWKITEMMKGYHSNITTPPELLNGNDSRDRDRDRERERER 346
             |:...|::.......|:....|:|       :|....:    |..:|....:....||:   :.
  Rat   322 NLDGTPALSTLGGFSPASKPSSPRE-------VKAEEKS----PVSINVKTVKKEPEDRQ---QA 372

  Fly   347 ERDPSSLLPPPAMVPQQRRQDGGHQRSSSVSGVPGSSSSSSSSSHKMPNYPGGMPPDAHTDHKSK 411
            .:.|.:.:          |:|....|:|..:....|.:.|.|.||         .|..|
  Rat   373 SKSPYNGV----------RKDSKRSRNSRSASRSRSRTRSRSRSH---------TPRRH------ 412

  Fly   412 QPGYNNRMPSSHQRSSSSGLGSSGSGSQRSSSSSSSSSQQPGRPSMPVDYHKSSRGMPPVGVGMP 476
               ||||      ||      .||:.|.||.|.|.|.|:.|.|      :|.
  Rat   413 ---YNNR------RS------RSGTYSSRSRSRSRSHSESPRR------HHN------------- 443

  Fly   477 PHGS-HKMTSGSKPQQPQQQPVPHPSASNSSASGMSSKDKSQSNKMYPNAPPPYSNSAPQNPLMS 540
             ||| |.....::..........|....:.|.|...::|.|...|.:.:....:.:...::....
  Rat   444 -HGSPHLKAKHTREDLKSSNRHGHKRKKSRSRSQSKTRDHSDVTKKHRHERGHHRDRRERSRSFE 507

  Fly   541 R---GGYPGASNGSQPPPPAGYGGHR 563
            |   |.:.|.|.       :|:|.||
  Rat   508 RSHKGKHHGGSR-------SGHGRHR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycT	NP_524127.2	CYCLIN_CCNT_rpt1	45..174	CDD:410241	39/137 (28%)
		CYCLIN_CCNT_rpt2	179..268	CDD:410242	30/110 (27%)
Ccnl1	NP_446114.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		14/29 (48%)
		CYCLIN_SF	41..196	CDD:477360	41/157 (26%)
		Cyclin-like 1	89..191		30/101 (30%)
		CYCLIN_SF	200..322	CDD:477360	36/128 (28%)
		Cyclin-like 2	204..288		22/87 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..527		57/281 (20%)
		RS	391..433		20/71 (28%)