Protein Alignment CG7542 and TPSB2

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 86/282 - (30%)
• Similarity: 140/282 - (49%)
• Gaps: 29/282 - (10%)

  Fly     1 MMKLLVCVL--LVGSCTAVP----LLTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTL 59
            |:.||:..|  |.....|.|    .|..|.  |..|:.|...::|:|..|.|....|..:|||:|
Human     1 MLNLLLLALPVLASRAYAAPAPGQALQRVG--IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63

  Fly    60 ISHYWIITAAHCMDGAESVTVYLGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVNDISLIR 124
            |...|::|||||: |.:...:....:.:.::....|:::: ..|.||||..:..:.:..||:|:.
Human    64 IHPQWVLTAAHCV-GPDVKDLAALRVQLREQHLYYQDQLL-PVSRIIVHPQFYTAQIGADIALLE 126

  Fly   125 LPAFVGFTDRIRAASLPRRLNGQFPTYESIRAFASGWGRESDASDSVSP--VLRYVEMPIMPHSL 187
            |...|..:..:...:|| ..:..||  ..:..:.:||| :.|..:.:.|  .|:.|::|||.:.:
Human   127 LEEPVNVSSHVHTVTLP-PASETFP--PGMPCWVTGWG-DVDNDERLPPPFPLKQVKVPIMENHI 187

  Fly   188 C-RMYWSGA--------VSEKMICMSTTSGKSTCHGDSGGPLVYKQGNSSYLIGSTSFGTSMGC- 242
            | ..|..||        |.:.|:|...|. :.:|.||||||||.|...:....|..|:|.  ||
Human   188 CDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGE--GCA 249

  Fly   243 QVGFPAVFTRISSYLDWILNHI 264
            |...|.::||::.|||||.:::
Human   250 QPNRPGIYTRVTYYLDWIHHYV 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	77/247 (31%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	76/245 (31%)