Protein Alignment CG7542 and KLK15

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 79/271 - (29%)
• Similarity: 117/271 - (43%)
• Gaps: 33/271 - (12%)

  Fly     1 MMKLLVCVLLVGSCTAVPLLTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWI 65
            |..||....|:.|..|    .|.:..:...|.|...| |:|..| ...|.::  ||.:|||.:|:
Human     1 MWLLLTLSFLLASTAA----QDGDKLLEGDECAPHSQ-PWQVAL-YERGRFN--CGASLISPHWV 57

  Fly    66 ITAAHCMDGAESVTVYLGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVNDISLIRLPAFVG 130
            ::||||.  :..:.|.||..|:  ...:|.|::.. .|.:|.|..|.|.:..|||.|:||.....
Human    58 LSAAHCQ--SRFMRVRLGEHNL--RKRDGPEQLRT-TSRVIPHPRYEARSHRNDIMLLRLVQPAR 117

  Fly   131 FTDRIRAASLPRRLNGQFPTYESIRAFASGWGRESD----------ASDSVSPVLRYVEMPIMPH 185
            ...::|.|.||.|.     .:.......||||..|.          :..|:...|....:.|:..
Human   118 LNPQVRPAVLPTRC-----PHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177

  Fly   186 SLCRMYWSGAVSEKMICMSTTS-GKSTCHGDSGGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAV 249
            :.|...:.|.::..|:|..... |..:|.||||||||.    ...|.|..|:|.........|.|
Human   178 TSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVC----GGILQGIVSWGDVPCDNTTKPGV 238

  Fly   250 FTRISSYLDWI 260
            :|::..||:||
Human   239 YTKVCHYLEWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	72/245 (29%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	70/241 (29%)