Protein Alignment CG7542 and PLG

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 56/262 - (21%)
• Similarity: 88/262 - (33%)
• Gaps: 70/262 - (26%)

  Fly    36 DSIMDTGNNNNLPTL-LKCNFPPYG------KDYPGGFATGRFSDGRVPSDLIAEKLGLAKTLPA 93
            |.::..|.......| ||||.....      ::...|..|......:...||:. ||..||...|
Human   280 DELLALGREKGNEILELKCNLENKKEEVLRLEEQMNGLKTSNEHLQKHVEDLLT-KLKEAKEQQA 343

  Fly    94 YM--------NPYLKPEDLLKGVTFASGGTGYDPLTAKIMSVISVWDQLINFKEYISKIKRHFGE 150
            .|        |.::|..:|.|...        |...||...:....|:|       .|:.:..||
Human   344 SMEEKFHNELNAHIKLSNLYKSAA--------DDSEAKSNELTRAVDEL-------HKLLKEAGE 393

  Fly   151 ------------EKAKDILEHSFFLVV-------SSSNDLAHTYLAQTHRYDRTSYANFLADSAV 196
                        |::||.:|......:       .::|||    |:.|.|           ..|:
Human   394 ANKTIQDHLLQVEESKDQMEKEMLEKIGKLEKELENANDL----LSATKR-----------KGAI 443

  Fly   197 HFVRELHKLGARKIGVFSAVPVGCVPLQRTVFGGFFTRGCNQPLNNMAKQFNARLSPALDSLDKE 261
            ....||..:......|...|..|   ::.|.....:....:|.|  :.||.|.|::..||.:.||
Human   444 LSEEELAAMSPTAAAVAKIVKPG---MKLTELYNAYVETQDQLL--LEKQENKRINKYLDEIVKE 503

  Fly   262 LD 263
            ::
Human   504 VE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	56/260 (22%)
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527	17/74 (23%)
		KR	375..456	CDD:214527	18/102 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416		4/19 (21%)
		KR	479..560	CDD:214527	10/29 (34%)
		Tryp_SPc	581..804	CDD:238113