Protein Alignment CG7542 and KLK1

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 88/284 - (30%)
• Similarity: 132/284 - (46%)
• Gaps: 39/284 - (13%)

  Fly     1 MMKLLVCVLL-VGSCTAVPLLTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTW-CGGTLISHY 63
            |..|::|:.| :|...|.|   .::..|..|...|....|:||.|.    ::||: |||.|:...
Human     1 MWFLVLCLALSLGGTGAAP---PIQSRIVGGWECEQHSQPWQAALY----HFSTFQCGGILVHRQ 58

  Fly    64 WIITAAHCMDGAESVTVYLGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVN---------- 118
            |::|||||:  :::..::||..|:.|:....|   .|..|....|..:..|.:.|
Human    59 WVLTAAHCI--SDNYQLWLGRHNLFDDENTAQ---FVHVSESFPHPGFNMSLLENHTRQADEDYS 118

  Fly   119 -DISLIRL--PAFVGFTDRIRAASLPRRLNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVEM 180
             |:.|:||  ||.. .||.::...||.    :.|...| ...|||||.....:.|....|:.|::
Human   119 HDLMLLRLTEPADT-ITDAVKVVELPT----EEPEVGS-TCLASGWGSIEPENFSFPDDLQCVDL 177

  Fly   181 PIMPHSLCRMYWSGAVSEKMICMS-TTSGKSTCHGDSGGPLVYKQGNSSYLIGSTSFGTSMGCQV 244
            .|:|:..|:......|::.|:|:. ...||.||.|||||||:.    ...|.|.||:|.......
Human   178 KILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMC----DGVLQGVTSWGYVPCGTP 238

  Fly   245 GFPAVFTRISSYLDWILNHIIAHN 268
            ..|:|..|:.||:.|| ...||.|
Human   239 NKPSVAVRVLSYVKWI-EDTIAEN 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	78/250 (31%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	78/251 (31%)