Protein Alignment CG7542 and HPN

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 70/265 - (26%)
• Similarity: 118/265 - (44%)
• Gaps: 40/265 - (15%)

  Fly    27 ITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMDGAESV----TVYLGAINI 87
            |..|....:|::|:|..|..   :.:..|||:|:|..|::|||||......|    .|:.||:
Human   163 IVGGRDTSLGRWPWQVSLRY---DGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV-- 222

  Fly    88 GDESEEGQERIMVEKSGIIVHSNYM------ASTVVNDISLIRLPAFVGFTDRIRAASLPRR--- 143
               ::.....:.:....::.|..|:      :....|||:|:.|.:.:..|:.|:...||..
Human   223 ---AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQA 284

  Fly   144 -LNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCR--MYWSGAVSEKMICMS- 204
             ::|:..|       .:|||.......... ||:...:||:.:.:|.  .::...:..||.|..
Human   285 LVDGKICT-------VTGWGNTQYYGQQAG-VLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 341

  Fly   205 TTSGKSTCHGDSGGPLVYKQGNSS----YLIGSTSFGTSMGCQVG-FPAVFTRISSYLDWILNHI 264
            ...|...|.||||||.|.:...|.    .|.|..|:||  ||.:. .|.|:|::|.:.:||...|
Human   342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGVYTKVSDFREWIFQAI 404

  Fly   265 IAHNK 269
            ..|::
Human   405 KTHSE 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	68/257 (26%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736
		Tryp_SPc	163..400	CDD:238113	66/254 (26%)