Protein Alignment CG7542 and GZMK

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 64/248 - (25%)
• Similarity: 115/248 - (46%)
• Gaps: 24/248 - (9%)

  Fly    27 ITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHC---MDGAESVTVYLGAINIG 88
            |..|:.......|:.|  ::.:|.... |||.||...|::|||||   ....:|.||.|||.::
Human    27 IIGGKEVSPHSRPFMA--SIQYGGHHV-CGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSL- 87

  Fly    89 DESEEGQERIMVEKSGIIVHSNYMASTVVNDISLIRLPAFVGFTDRIRAASLPRRLNGQFPTYES 153
            .::|..::.:.::|  .|..|...:....|||.|::|.........::...:..:.:.:..|
Human    88 SKNEASKQTLEIKK--FIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSGT--- 147

  Fly   154 IRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLC--RMYWSG--AVSEKMICMSTTSG-KSTCH 213
             :...:|||.....|...|..||.|.:.::...||  :.|::|  .:::.|:|.....| |.:|.
Human   148 -KCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCK 211

  Fly   214 GDSGGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRIS-SYLDWILNHII 265
            |||||||:.|....:.:.|....|.:..     |.::|.:: .|..||.::::
Human   212 GDSGGPLICKGVFHAIVSGGHECGVATK-----PGIYTLLTKKYQTWIKSNLV 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	64/244 (26%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	64/244 (26%)