Protein Alignment CG7542 and KLK5

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 68/247 - (27%)
• Similarity: 107/247 - (43%)
• Gaps: 15/247 - (6%)

  Fly    22 DVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMDGAESVTVYLGAIN 86
            |....|.||...::...|:||.|.:...  ..:||..|:...|::|||||.  .:...|.||..:
Human    62 DSSSRIINGSDCDMHTQPWQAALLLRPN--QLYCGAVLVHPQWLLTAAHCR--KKVFRVRLGHYS 122

  Fly    87 IGDESEEGQERIMVEKSGIIVHSNYMASTVVNDISLIRLPAFVGFTDRIRAASLPRRLNGQFPTY 151
            :....|.||:.....||  |.|..|......||:.||:|...:..|..:|    |..::...|:
Human   123 LSPVYESGQQMFQGVKS--IPHPGYSHPGHSNDLMLIKLNRRIRPTKDVR----PINVSSHCPS- 180

  Fly   152 ESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCRMYWSGAVSEKMICMSTTSGKSTCHGDS 216
            ...:...||||...........||:.:.:.::....|...:...:.:.|.|....:|:.:|.|||
Human   181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDS 245

  Fly   217 GGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRISSYLDWILNHIIAHN 268
            |||:|.   |.| |.|..|:|.....:...|.|:|.:..:..||...|.|::
Human   246 GGPVVC---NGS-LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	65/235 (28%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/5 (20%)
		Tryp_SPc	66..285	CDD:214473	63/233 (27%)