Protein Alignment CG7542 and F12

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 71/301 - (23%)
• Similarity: 117/301 - (38%)
• Gaps: 75/301 - (24%)

  Fly    16 AVPLLTDVEPYITNGEPAEVGQ----------------------FPYQAGLNVSFGNWS-TWCGG 57
            |:|...:..|.:|...|...||                      .||.|.|     .|. ::|.|
Human   340 ALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAAL-----YWGHSFCAG 399

  Fly    58 TLISHYWIITAAHCMD---GAESVTVYLGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVND 119
            :||:..|::|||||:.   ..|.:||.||........|..|   .:......:|..:...:..:|
Human   400 SLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQ---TLAVRSYRLHEAFSPVSYQHD 461

  Fly   120 ISLIRLP-----AFVGFTDRIRAASLPRRLNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVE 179
            ::|:||.     :....:..::...||   :|.....|:.....:|||.:.:.::..:..|:..:
Human   462 LALLRLQEDADGSCALLSPYVQPVCLP---SGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQ 523

  Fly   180 MP----------------IMPHSLCRMYWSGAVSEKMICMSTTSGKSTCHGDSGGPLVYKQGNSS 228
            :|                |:|..||..:..|             |...|.||||||||.:...:.
Human   524 VPFLSLERCSAPDVHGSSILPGMLCAGFLEG-------------GTDACQGDSGGPLVCEDQAAE 575

  Fly   229 ---YLIGSTSFGTSMGCQVGFPAVFTRISSYLDWILNHIIA 266
               .|.|..|:|:..|.: ..|.|:|.::.||.||..|.::
Human   576 RRLTLQGIISWGSGCGDR-NKPGVYTDVAYYLAWIREHTVS 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	67/285 (24%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359		5/18 (28%)
		Tryp_SPc	373..612	CDD:238113	63/263 (24%)