Protein Alignment CG7542 and KLK8

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 74/241 - (30%)
• Similarity: 112/241 - (46%)
• Gaps: 22/241 - (9%)

  Fly    24 EPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMDGAESVTVYLGAINIG 88
            |..:..|...:....|:||.|   |......|||.|:...|::|||||.  ....||.||..::
Human    75 EDKVLGGHECQPHSQPWQAAL---FQGQQLLCGGVLVGGNWVLTAAHCK--KPKYTVRLGDHSL- 133

  Fly    89 DESEEGQER-IMVEKSGIIVHSNYMASTVV---NDISLIRLPAFVGFTDRIRAASLPRRLNGQFP 149
             ::::|.|: |.|.:|  |.|..|.:|.|.   :|:.|::|........:::..||     ....
Human   134 -QNKDGPEQEIPVVQS--IPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL-----ADHC 190

  Fly   150 TYESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCRMYWSGAVSEKMICMSTTSGKSTCHG 214
            |....:...||||..:...::....|...|:.|.|...|...:.|.:::.|:|..::.|..||.|
Human   191 TQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQG 255

  Fly   215 DSGGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRISSYLDWI 260
            |||||||.    ...|.|.||:|:....:...|.|:|.|..|||||
Human   256 DSGGPLVC----DGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	73/238 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	71/237 (30%)