Protein Alignment CG7542 and PRSS21

DIOPT Version :10

• Sequence 1: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 86/300 - (28%)
• Similarity: 134/300 - (44%)
• Gaps: 68/300 - (22%)

  Fly     4 LLVCVLLVGSCTAVPLLTDVEPY------------ITNGEPAEVGQFPYQAGLNVSFGNW-STWC 55
            ||:.:||..:....|...:..|.            |..||.||:|::|:|..|.:    | |..|
Human     7 LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRL----WDSHVC 67

  Fly    56 GGTLISHYWIITAAHCMDGAESVTVYLGAINIGDES----EEGQ--------------ERIMVEK 102
            |.:|:||.|.:|||||.:...         ::.|.|    :.||              .|..|
Human    68 GVSLLSHRWALTAAHCFETYS---------DLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFV-- 121

  Fly   103 SGIIVHSNYMASTVVNDISLIRLPAFVGFTDRIRAASLPRRLNGQFPTYE---SIRAFASGWG-- 162
            |.|.:...|:.::.. ||:|::|.|.|.:|..|:...|      |..|:|   ....:.:|||
Human   122 SNIYLSPRYLGNSPY-DIALVKLSAPVTYTKHIQPICL------QASTFEFENRTDCWVTGWGYI 179

  Fly   163 RESDASDSVSPVLRYVEMPIMPHSLC-----RMYWSGAVSEKMICM-STTSGKSTCHGDSGGPLV 221
            :|.:|..| ...|:.|::.|:.:|:|     :..:...:...|:|. :...||..|.|||||||.
Human   180 KEDEALPS-PHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLA 243

  Fly   222 YKQGNSSYLIGSTSFGTSMGC-QVGFPAVFTRISSYLDWI 260
            ..:....|.||..|:|  :|| :...|.|:|.||.:.:||
Human   244 CNKNGLWYQIGVVSWG--VGCGRPNRPGVYTNISHHFEWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	79/264 (30%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	79/264 (30%)