Protein Alignment LLGL1 and SRO7

DIOPT Version :9

• Sequence 1: XP_011522151.1
• Gene: LLGL1 / 3996
• HGNCID: 6628
• Length: 1105
• Species: Homo sapiens
• Sequence 2: NP_015357.1
• Gene: SRO7 / 856144
• SGDID: S000006236
• Length: 1033
• Species: Saccharomyces cerevisiae
• Alignment Length: 1063
• Identity: 206/1063 - (19%)
• Similarity: 370/1063 - (34%)
• Gaps: 330/1063 - (31%)

Human    19 KQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHF 83
            |.::|:..:|.::|..::|.|.|||....::||.|.:|.|.|||...||......|.:.:.:|.|
Yeast    62 KNKIFSLAETNKYGMSSKPIAAAFDFTQNLLAIATVTGEVHIYGQQQVEVVIKLEDRSAIKEMRF 126

Human    84 LTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQLPSR---PGFDGASAPLSLTRVTVVLLV 145
            :.|            ::| .:::.....::....|.::.:.   ||           ::|.:...
Yeast   127 VKG------------IYL-VVINAKDTVYVLSLYSQKVLTTVFVPG-----------KITSIDTD 167

Human   146 AASDIAALGTEGSSVFFLDVT-------TLTLLEGQTLAPGEVLRSVPDDYRCGKALGPVESLQG 203
            |:.|...:|.:..|:...|:.       .|..|:..:..|             ...|.|:.|:|.
Yeast   168 ASLDWMLIGLQNGSMIVYDIDRDQLSSFKLDNLQKSSFFP-------------AARLSPIVSIQW 219

Human   204 HLRDPTKILIGYSRGLL---VIWNQASQCV-----------DHIFLGNQQ-----LESLCWGRDS 249
            :.||...:||.|....|   ::.|:..|..           |.....|::     ::|| :..:|
Yeast   220 NPRDIGTVLISYEYVTLTYSLVENEIKQSFIYELPPFAPGGDFSEKTNEKRTPKVIQSL-YHPNS 283

Human   250 STVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFP---------CKAINKILWRNCESGGHF 305
            ..:::.|.|.|...|..::|.....:....|....|.|         ...|:|:.|. ||:...:
Yeast   284 LHIITIHEDNSLVFWDANSGHMIMARTVFETEINVPQPDYIRDSSTNAAKISKVYWM-CENNPEY 347

Human   306 IIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTR-PEDEFDDPQALAVL-LEEE 368
            ..........|.||...:      |::.|.:|.|    :::.|.. .::.:.:|:.:.:. |...
Yeast   348 TSLLISHKSISRGDNQSL------TMIDLGYTPR----YSITSYEGMKNYYANPKQMKIFPLPTN 402

Human   369 LVVLDLQTPGWPAVP--APYLAPLHSSA------------------------------------- 394
            :.::::.     .:|  :||.|..|:..
Yeast   403 VPIVNIL-----PIPRQSPYFAGCHNPGLILLILGNGEIETMLYPSGIFTDKASLFPQNLSWLRP 462

Human   395 ITCSAHVASVPAKLWARIVSAGEQQSPQPVSSALSWPITGG-RNLAQE-PSQRG-LLLTGHEDGT 456
            :..::..||||.|||...:||.:.:         .:.:.|| |...|: |::.| ..:|||.:|:
Yeast   463 LATTSMAASVPNKLWLGALSAAQNK---------DYLLKGGVRTKRQKLPAEYGTAFITGHSNGS 518

Human   457 VRFWDASGVALRPLYKLSTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVA 521
            ||.:|||                     |.|....|:.:       |......:....|.|.|::
Yeast   519 VRIYDAS---------------------HGDIQDNASFE-------VNLSRTLNKAKELAVDKIS 555

Human   522 LCKYTAQMVVAGTAGQVLVLELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAG 586
            ....|.::.|:...|.|::.:..   |.|..||      ::|            |.:|.|
Yeast   556 FAAETLELAVSIETGDVVLFKYE---VNQFYSV------ENR------------PESGDL----- 594

Human   587 FQPRVLVQCLPPAAVTAVTLHTEWSLVAFGTSHGFG-LFDYQRKSPVLARCTLHPNDSL-AMEGP 649
                                  |.:...|..::..| |.|.:.::|...|....|:.:: |.:|.
Yeast   595 ----------------------EMNFRRFSLNNTNGVLVDVRDRAPTGVRQGFMPSTAVHANKGK 637

Human   650 LSRVKSLKKSLRQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRS 714
            .|              .|..|.: |....|.|:..|     .|.::..|..:.|..:      |.
Yeast   638 TS--------------AINNSNI-GFVGIAYAAGSL-----MLIDRRGPAIIYMENI------RE 676

Human   715 ADDSLSGVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLG 779
            ...:.|..|.|:.|......|..:....|..||:.|.|..|.: :||:  ||:
Yeast   677 ISGAQSACVTCIEFVIMEYGDDGYSSILMVCGTDMGEVITYKI-LPAS--GGK------------ 726

Human   780 KEVQLM------HRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQG-------GHAVLIASEE 831
            .:||||      .:.|:..|.......:        |..||..|.||.       ...|||...:
Yeast   727 FDVQLMDITNVTSKGPIHKIDAFSKETK--------SSCLATIPKMQNLSKGLCIPGIVLITGFD 783

Human   832 QFKVFTLPKVSAKTKFKLTAHEGCR--VRKVALATFASVACEDYAE--TCLACLTNLGDVHVFSV 892
            ..::.||    .|:|   :.|:|.:  :....|:..::|...:..:  |.:..|...|.:.||::
Yeast   784 DIRLITL----GKSK---STHKGFKYPLAATGLSYISTVEKNNDRKNLTVIITLEINGHLRVFTI 841

Human   893 PGLRPQVHYSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEP--LCSLDINWPR 955
            |..:.|:                              ||...|.::|:.|||.  |.:.||....
Yeast   842 PDFKEQM------------------------------SEHIPFPIAAKYITESSVLRNGDIAIRV 876

Human   956 DATQASY--RIRESPKLSQANGT 976
            ...|||.  .::|...|:..:.|
Yeast   877 SEFQASLFSTVKEQDTLAPVSDT 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LLGL1	XP_011522151.1	LLGL	280..379	CDD:285555	18/109 (17%)
SRO7	NP_015357.1	Lgl_C	548..943	CDD:400768	97/486 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159051075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1983
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10241
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840