Protein Alignment LLGL1 and SPAC1F3.03

DIOPT Version :9

• Sequence 1: XP_011522151.1
• Gene: LLGL1 / 3996
• HGNCID: 6628
• Length: 1105
• Species: Homo sapiens
• Sequence 2: NP_593006.1
• Gene: SPAC1F3.03 / 2542372
• PomBaseID: SPAC1F3.03
• Length: 1004
• Species: Schizosaccharomyces pombe
• Alignment Length: 643
• Identity: 129/643 - (20%)
• Similarity: 229/643 - (35%)
• Gaps: 177/643 - (27%)

Human    32 GFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDD 96
            ||...|.....|.:..::||.:.:..:.|||...|: :.:..|.:|:  :|.......|:.:...
pombe    39 GFSLNPVLWCLDHQQGLLAIVSSTNRIYIYGKQHVQ-SVIVPDCSTI--VHIALCAAYLIVIDSR 100

Human    97 SSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPLSLTRVTVVLLVAASDIAALGTEGSSVF 161
            :::..:.::.|...            |:|    |:......:||..:.....|....|....||.
pombe   101 NTVLSYPLMKHRDL------------SKP----AATYFLKQKVTCTVTDPTIDWVFFGMSDGSVV 149

Human   162 FLDVTTLTL-----------------LEGQTLAPGEVLRSVPDDYRCGKALGPVESLQGHLRDPT 209
            ..|||...|                 :.|.:.||      ||     || |.||.|:|.|.:|..
pombe   150 PWDVTRHCLGKFKVPNLYVPRHEEWRMMGYSYAP------VP-----GK-LSPVVSVQIHPKDLG 202

Human   210 KILIGYSRGLLVIWNQASQCVDHIFL----GNQQ------------LESLCWGRDSSTVVSSHSD 258
            .|||.|..|:::...:..:.:....|    |:..            ::.:.|.......||.::|
pombe   203 VILIAYPDGVVLYSIRTDEVIRFYELEYAPGSTAAVLSPHNYRRPIVKGIEWSPWGDHFVSYYTD 267

Human   259 GSYAVWSVDAGSFPT-----LQPTVAT-TPYGPFPCKA----INKILWRNCESGG-HFIIFSGGM 312
            .::|.|.||. .:|.     :...:.| ||....|.|.    |..:.|..||... .||:..||:
pombe   268 STFAFWDVDQ-EYPVQVRNFVDSNIHTYTPMQRNPPKTELEPIRSMRWCCCEDPTVSFILMLGGL 331

Human   313 PRAS-------YGDRHCVSVLRAETLVTLDFTSR--------------IIDFFTVHSTRPE-DEF 355
            |:.:       :..|:..:....||..  :|.:.              :.|...:.|:.|. :..
pombe   332 PKEAPVKGISLFSYRNLPAKKDVETFA--EFFANPNSQRFFPFIDIPPVRDMLVIPSSSPHYNGS 394

Human   356 DDPQALAVLLEE-ELVVLDLQTPGWP----AVPAPYLAPLHSSAITCSAHVASVPAKLWARI--- 412
            .:|:.|.:|.|: .|.:||:.|....    ::| |.|..|.|.....:  ..:|..|:|.:|
pombe   395 HNPKNLLLLSEDNSLSLLDISTGNISNMSLSIP-PSLCFLASDFRVIA--FQTVTKKVWNQIEDT 456

Human   413 VSAGEQQ------SPQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDG-TVRFWDASGVALRP- 469
            :|.....      ||.|             ...::..:|.||:|  ..| ::..||.|...:.|
pombe   457 ISVNSHYSCLFGGSPSP-------------GYLKKLDERNLLIT--STGLSLSIWDISQGFMNPS 506

Human   470 -LYKLSTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCK-------YT 526
             ...|..:.:.:.....:..:..|:...:.|  :..|.|.:.        :|.:||       ..
pombe   507 LCVNLDFSSVMRKHLTPSAFITTASFSTYNP--EFSCADSFG--------RVIVCKRKNHKENLP 561

Human   527 AQ-----------MVVAGT----------AGQVLVLELSDVPV----EQAVSVAIIDL 559
            ||           :|:.||          .|:|.:.::|::..    .|...:.|||:
pombe   562 AQLANGIYRLDDTLVLEGTLHAQYYIDLKRGRVTLNQMSNIGFVCIGYQDGGITIIDM 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LLGL1	XP_011522151.1	LLGL	280..379	CDD:285555	29/127 (23%)
SPAC1F3.03	NP_593006.1	WD40	45..283	CDD:295369	55/269 (20%)
		WD40 repeat	45..79	CDD:293791	7/34 (21%)
		WD40 repeat	85..122	CDD:293791	6/52 (12%)
		WD40 repeat	127..185	CDD:293791	13/63 (21%)
		WD40 repeat	192..229	CDD:293791	9/36 (25%)
		WD40 repeat	249..297	CDD:293791	11/48 (23%)
		WD40 repeat	309..359	CDD:293791	12/51 (24%)
		Lgl_C	524..899	CDD:285762	19/106 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1983
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10241
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000