Protein Alignment LLGL1 and sro7

DIOPT Version :10

• Sequence 1: XP_011522151.1
• Gene: LLGL1 / 3996
• HGNCID: 6628
• Length: 1105
• Species: Homo sapiens
• Sequence 2: NP_593006.1
• Gene: sro7 / 2542372
• PomBaseID: SPAC1F3.03
• Length: 1004
• Species: Schizosaccharomyces pombe
• Alignment Length: 643
• Identity: 129/643 - (20%)
• Similarity: 229/643 - (35%)
• Gaps: 177/643 - (27%)

Human    32 GFPNQPSALAFDPELRIMAIGTRSGAVKIYGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDD 96
            ||...|.....|.:..::||.:.:..:.|||...|: :.:..|.:|:  :|.......|:.:...
pombe    39 GFSLNPVLWCLDHQQGLLAIVSSTNRIYIYGKQHVQ-SVIVPDCSTI--VHIALCAAYLIVIDSR 100

Human    97 SSLHLWEIVHHNGCAHLEEALSFQLPSRPGFDGASAPLSLTRVTVVLLVAASDIAALGTEGSSVF 161
            :::..:.::.|...            |:|    |:......:||..:.....|....|....||.
pombe   101 NTVLSYPLMKHRDL------------SKP----AATYFLKQKVTCTVTDPTIDWVFFGMSDGSVV 149

Human   162 FLDVTTLTL-----------------LEGQTLAPGEVLRSVPDDYRCGKALGPVESLQGHLRDPT 209
            ..|||...|                 :.|.:.||      ||     || |.||.|:|.|.:|..
pombe   150 PWDVTRHCLGKFKVPNLYVPRHEEWRMMGYSYAP------VP-----GK-LSPVVSVQIHPKDLG 202

Human   210 KILIGYSRGLLVIWNQASQCVDHIFL----GNQQ------------LESLCWGRDSSTVVSSHSD 258
            .|||.|..|:::...:..:.:....|    |:..            ::.:.|.......||.::|
pombe   203 VILIAYPDGVVLYSIRTDEVIRFYELEYAPGSTAAVLSPHNYRRPIVKGIEWSPWGDHFVSYYTD 267

Human   259 GSYAVWSVDAGSFPT-----LQPTVAT-TPYGPFPCKA----INKILWRNCESGG-HFIIFSGGM 312
            .::|.|.||. .:|.     :...:.| ||....|.|.    |..:.|..||... .||:..||:
pombe   268 STFAFWDVDQ-EYPVQVRNFVDSNIHTYTPMQRNPPKTELEPIRSMRWCCCEDPTVSFILMLGGL 331

Human   313 PRAS-------YGDRHCVSVLRAETLVTLDFTSR--------------IIDFFTVHSTRPE-DEF 355
            |:.:       :..|:..:....||..  :|.:.              :.|...:.|:.|. :..
pombe   332 PKEAPVKGISLFSYRNLPAKKDVETFA--EFFANPNSQRFFPFIDIPPVRDMLVIPSSSPHYNGS 394

Human   356 DDPQALAVLLEE-ELVVLDLQTPGWP----AVPAPYLAPLHSSAITCSAHVASVPAKLWARI--- 412
            .:|:.|.:|.|: .|.:||:.|....    ::| |.|..|.|.....:  ..:|..|:|.:|
pombe   395 HNPKNLLLLSEDNSLSLLDISTGNISNMSLSIP-PSLCFLASDFRVIA--FQTVTKKVWNQIEDT 456

Human   413 VSAGEQQ------SPQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDG-TVRFWDASGVALRP- 469
            :|.....      ||.|             ...::..:|.||:|  ..| ::..||.|...:.|
pombe   457 ISVNSHYSCLFGGSPSP-------------GYLKKLDERNLLIT--STGLSLSIWDISQGFMNPS 506

Human   470 -LYKLSTAGLFQTDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCK-------YT 526
             ...|..:.:.:.....:..:..|:...:.|  :..|.|.:.        :|.:||       ..
pombe   507 LCVNLDFSSVMRKHLTPSAFITTASFSTYNP--EFSCADSFG--------RVIVCKRKNHKENLP 561

Human   527 AQ-----------MVVAGT----------AGQVLVLELSDVPV----EQAVSVAIIDL 559
            ||           :|:.||          .|:|.:.::|::..    .|...:.|||:
pombe   562 AQLANGIYRLDDTLVLEGTLHAQYYIDLKRGRVTLNQMSNIGFVCIGYQDGGITIIDM 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LLGL1	XP_011522151.1	LLGL	280..380	CDD:462446	29/128 (23%)
sro7	NP_593006.1	WD40	45..283	CDD:475233	55/269 (20%)
		Lgl_C	524..899	CDD:400768	19/106 (18%)