DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and st14b

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	267	Identity:	88/267 - (32%)
Similarity:	125/267 - (46%)	Gaps:	55/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITY--------Y 87
            ||.||:.:...::|:||.|.::....:   ||||:||:.:|:||||||:......|        |
Zfish   624 RIVGGKDSDEGEWPWQVSLHMKTQGHV---CGASVISNSWLVTAAHCVQDNDQFRYSQADQWEVY 685

  Fly    88 LG-------------GVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRP 139
            ||             .|||:.|             ||.::..|.:|||||:.|.....|..:|.|
Zfish   686 LGLHNQGETSKSTQRSVLRIIP-------------HPQYDHSSYDNDIALMELDSPVTLNQNIWP 737

  Fly   140 IRLPGLSSSRNSYDYVPAIAS----GWGRMNDESTAISDNLRYV-YRFVESNEDCEYSYANIKPT 199
            |.||      :...|.||..|    |||::.:.|.|:...|:.. .|.:.|....:.....|.|.
Zfish   738 ICLP------DPTHYFPAGKSVWITGWGKLREGSDAVPSVLQKAEVRIINSTVCSKLMDDGITPH 796

  Fly   200 NICMDT-TGGKSTCTGDSGGPLVYSDPVQNADI-LIGVTSYGKKSGC-TKGYPSVFTRITAYLDW 261
            .||... :||...|.||||||:  |....|..: |.||.|:|  .|| .:..|.|:||:|.|..|
Zfish   797 MICAGVLSGGVDACQGDSGGPM--SSIEGNGRMFLAGVVSWG--DGCGRRNRPGVYTRVTDYRSW 857

  Fly   262 IGEVSGV 268
            |.|::|:
Zfish   858 IREITGI 864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	84/259 (32%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060
		Tryp_SPc	624..858	CDD:214473	84/259 (32%)
		Tryp_SPc	625..861	CDD:238113	85/261 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920