DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Prss36

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	259	Identity:	83/259 - (32%)
Similarity:	117/259 - (45%)	Gaps:	41/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHC------VEKAVAITYYLG 89
            ||.||..|....:|:||  |:.:.....  ||.|||:..::|:||||      :|.|..::..||
Mouse    47 RIVGGSDAHPGTWPWQV--SLHQGGGHI--CGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLG 107

  Fly    90 GVLRLAPRQLIRSTNPEVHLHPD-WNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYD 153
            ...:..|.:.....:....|.|| ::...|..|:||:||...|.|..|:||:.||     |.|:.
Mouse   108 VHSQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVRPVCLP-----RASHL 167

  Fly   154 YVPAI---ASGWGRMNDESTAISDNLRYVYRFVE----SNEDCEYSYANIKPTNICMD------- 204
            :....   |:|||   |...|:...|.:|.:.||    ....|:..|:...|.|:...
Mouse   168 FAHGTACWATGWG---DVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLC 229

  Fly   205 ---TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGC-TKGYPSVFTRITAYLDWIGE 264
               ..|.:.||.||||||||..|  .....|.|:||:|  .|| .:..|.|||.:..|..||.|
Mouse   230 AGYPAGRRDTCQGDSGGPLVCED--GGRWFLAGITSFG--FGCGRRNRPGVFTAVAPYESWIRE 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	80/255 (31%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	82/258 (32%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010