DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and tmprss4

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_012822151.1	Gene:	tmprss4 / 733869	XenbaseID:	XB-GENE-940762	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	269	Identity:	77/269 - (28%)
Similarity:	122/269 - (45%)	Gaps:	52/269 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SISCLDMGHG-IGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKA 81
            |:.|...|.| ...||.||..:...::|:||.|.....:    .||.|:::.|::|.||||.::.
Frog   537 SLRCAACGTGHKQERIIGGSNSDILKYPWQVSLQYMGQH----ICGGSILNSRWILCAAHCFDRG 597

  Fly    82 -------------VAITYYLGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALL 133
                         ..:||..|..:            .::.|:..:......|||||::|..|.:.
Frog   598 QRQVDRWRVQYGITTLTYLFGTFV------------DKIFLNSKYVTDQKPNDIALLQLKSDIVA 650

  Fly   134 CDSIRPIRLPGLSSSRNSYD---YVPAI--ASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSY 193
            ..|::|:.|||       ||   .|.|:  .:|||...:...|::..|:.|...:.|:..|...|
Frog   651 SASVQPVCLPG-------YDNNLVVGAVLYVTGWGHTVEGGAALASQLQEVAISLISSTTCNQEY 708

  Fly   194 -ANIKPTNICM-DTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPS---VFT 253
             ..|..|.:|. ...||..||.||||||||......:.: .:|:.|:|  .||  |.|:   |:|
Frog   709 GGQILDTMLCAGKIAGGADTCQGDSGGPLVSLGQSSHWE-QVGIVSWG--DGC--GRPNRVGVYT 768

  Fly   254 RITAYLDWI 262
            .:.::|:||
Frog   769 DVQSFLNWI 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	71/253 (28%)
tmprss4	XP_012822151.1	ATF7IP_BD	<110..233	CDD:293393
		PHA03193	<206..340	CDD:177555
		LDLa	402..434	CDD:238060
		SRCR_2	453..545	CDD:292133	2/7 (29%)
		SRCR	464..541	CDD:278931	1/3 (33%)
		Tryp_SPc	551..777	CDD:214473	71/253 (28%)
		Tryp_SPc	552..777	CDD:238113	70/252 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000