DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and st14a

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001035441.2	Gene:	st14a / 678603	ZFINID:	ZDB-GENE-030131-6496	Length:	834	Species:	Danio rerio

Alignment Length:	256	Identity:	79/256 - (30%)
Similarity:	119/256 - (46%)	Gaps:	35/256 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLGGVLRL- 94
            ||.||:.|...:||:||.|.|:....:   ||.|:|::|:::||||||:..|.|.|...|...:
Zfish   596 RIVGGQDAFEGEFPWQVSLHIKNIAHV---CGGSIINERWIVTAAHCVQDDVKIKYSQPGTWEVF 657

  Fly    95 -----------APRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSS 148
                       |.::|::...|    ||.:|..:.:|||||:.:.......|:|||:.||
Zfish   658 LGLHSQKDKLTATKRLLKQVIP----HPYYNAYTYDNDIALMEMESPVTFSDTIRPVCLP----- 713

  Fly   149 RNSYDYVPA----IASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYANIKPTNICMDT-TGG 208
             .:.|..||    ..||||...:..:..:...:...|.:.|....:.....|.....|... :||
Zfish   714 -TATDTFPAGTSVFISGWGATREGGSGATVLQKAEVRIINSTVCNQLMGGQITSRMTCAGVLSGG 777

  Fly   209 KSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCT-KGYPSVFTRITAYLDWIGEVSGV 268
            ...|.|||||||  |.|......|.||.|:|  .||. :..|.:::.:..:..||.|.:||
Zfish   778 VDACQGDSGGPL--SFPSGKRMFLAGVVSWG--DGCARRNKPGIYSNVPKFRAWIKEKTGV 834

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	74/248 (30%)
st14a	NP_001035441.2	SEA	77..168	CDD:279699
		CUB	219..322	CDD:238001
		CUB	329..431	CDD:238001
		LDLa	443..472	CDD:238060
		LDLa	474..508	CDD:238060
		LDLa	510..544	CDD:238060
		LDLa	550..585	CDD:238060
		Tryp_SPc	596..828	CDD:214473	74/248 (30%)
		Tryp_SPc	597..831	CDD:238113	75/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920