Protein Alignment Jon74E and CELA2A

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_254275.1
• Gene: CELA2A / 63036
• HGNCID: 24609
• Length: 269
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 97/285 - (34%)
• Similarity: 141/285 - (49%)
• Gaps: 43/285 - (15%)

  Fly     3 ISTILVFLLILVQGRSISCLDMGH-GIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLI 66
            |.|:|  |..||.| ::||.|..: ....|:.|||.||.|.:|:||.|........|..||.|||
Human     2 IRTLL--LSTLVAG-ALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLI 63

  Fly    67 SDRYLLTAAHCVEKAVAITYYLG-----------GVLRLAPRQLIRSTNPEVHLHPDWNCQSLE- 119
            ::.::||||||:..  :.||.:|           |.|.::..:::        :|.|||...:.
Human    64 ANSWVLTAAHCISS--SRTYRVGLGRHNLYVAESGSLAVSVSKIV--------VHKDWNSNQISK 118

  Fly   120 -NDIALVRLPEDALLCDSIRPIRLPGLSS-SRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRF 182
             |||||::|.....|.|.|:...||...: ..|:|   |...:||||:.... |:.|.|:.....
Human   119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNY---PCYVTGWGRLQTNG-AVPDVLQQGRLL 179

  Fly   183 VESNEDCEYSY---ANIKPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNAD---ILIGVTSYGKK 241
            |.....|..|.   :::|.:.||....|..|:|.|||||||    ..|.:|   .:.|:.|:|.:
Human   180 VVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPL----NCQASDGRWQVHGIVSFGSR 240

  Fly   242 SGCTKGY-PSVFTRITAYLDWIGEV 265
            .||...: ||||||::.|:|||..|
Human   241 LGCNYYHKPSVFTRVSNYIDWINSV 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	84/251 (33%)
CELA2A	NP_254275.1	Tryp_SPc	29..265	CDD:238113	85/253 (34%)