Protein Alignment Jon74E and TMPRSS15

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001414985.1
• Gene: TMPRSS15 / 5651
• HGNCID: 9490
• Length: 1064
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 88/270 - (32%)
• Similarity: 127/270 - (47%)
• Gaps: 51/270 - (18%)

  Fly    16 GRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMY---CWCGASLISDRYLLTAAHC 77
            |:.::..|    |..:|.||..|:...:|:.|||       .|   ..|||||:|..:|::||||
Human   818 GKKLAAQD----ITPKIVGGSNAKEGAWPWVVGL-------YYGGRLLCGASLVSSDWLVSAAHC 871

  Fly    78 V-------EKAVAITYYLGGVLR--LAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALL 133
            |       .|..||   ||..::  |...|.:.....|:.::|.:|.:..:||||::.|......
Human   872 VYGRNLEPSKWTAI---LGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNY 933

  Fly   134 CDSIRPIRLPG----LSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDC----- 189
            .|.|:||.||.    ....||.     :|| |||.:..:.|. ::.|:.....:.|||.|
Human   934 TDYIQPICLPEENQVFPPGRNC-----SIA-GWGTVVYQGTT-ANILQEADVPLLSNERCQQQMP 991

  Fly   190 EYSYANIKPTNICMD-TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCT-KGYPSVF 252
            ||   ||....||.. ..||..:|.|||||||:..:  .|...|.||||:|.|  |. ...|.|:
Human   992 EY---NITENMICAGYEEGGIDSCQGDSGGPLMCQE--NNRWFLAGVTSFGYK--CALPNRPGVY 1049

  Fly   253 TRITAYLDWI 262
            .|::.:.:||
Human  1050 ARVSRFTEWI 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	83/253 (33%)
TMPRSS15	NP_001414985.1	None