DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jon74E and KLK7

DIOPT Version :9

Sequence 1:NP_001189126.2 Gene:Jon74E / 39959 FlyBaseID:FBgn0023197 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_005037.1 Gene:KLK7 / 5650 HGNCID:6368 Length:253 Species:Homo sapiens


Alignment Length:243 Identity:71/243 - (29%)
Similarity:108/243 - (44%) Gaps:19/243 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 GGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLGGVLR 93
            |.:|..|........|:||.|.  ..|.::  ||..|:::|::||||||  |....|.:||.. .
Human    27 GDKIIDGAPCARGSHPWQVALL--SGNQLH--CGGVLVNERWVLTAAHC--KMNEYTVHLGSD-T 84

  Fly    94 LAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAI 158
            |..|:..|....:...||.::.|:..||:.||:|...|.|...::.:|||    ||.........
Human    85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP----SRCEPPGTTCT 145

  Fly   159 ASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYAN-IKPTNICMDTTGG-KSTCTGDSGGPLV 221
            .||||...........:|..|...:.|.:||...|.: ::.:.:|...... |:.|.||||||||
Human   146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLV 210

  Fly   222 YSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDWIGEVSGVH 269
            ....:|      |:.|:|.........|.|:|::..:..||.:....|
Human   211 CRGTLQ------GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Jon74ENP_001189126.2 Tryp_SPc 31..262 CDD:214473 67/232 (29%)
KLK7NP_005037.1 Tryp_SPc 29..245 CDD:214473 67/232 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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