DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and tmprss9

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	259	Identity:	78/259 - (30%)
Similarity:	118/259 - (45%)	Gaps:	45/259 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVE---KAVAITYYLGGVL 92
            ||.||..||..::|:...|..:..:.    |||:||..::|||||||..   .....|..||.|:
Zfish   556 RIIGGVTARRGEWPWVGSLQYQRIHR----CGATLIHCKWLLTAAHCFRGDLNPAGYTVSLGSVI 616

  Fly    93 ------------RLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGL 145
                        |:.|             ||.:|..:::.|:|||.:...|....:|:.:.||
Zfish   617 WSGLGALVIPVQRIIP-------------HPAFNSSTMDLDVALVEISIPAPKSYTIQTVCLP-- 666

  Fly   146 SSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSY-ANIKPTNICMD-TTGG 208
            |...:....:.....|||.:.::. .|::.|:.....|....||:.:| |.:....:|.. ..|.
Zfish   667 SPWHSFIKSMECYIIGWGAVREDG-MITNLLQKAQVGVIDQSDCQRAYGAELTDNMMCAGYMEGQ 730

  Fly   209 KSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTK-GYPSVFTRITAYLDWIGEVSGVHYP 271
            :.||.||||||||..:.: ....|.||||:|  .||.: |:|.|:.|.||..:||    .:|.|
Zfish   731 RDTCLGDSGGPLVCRETL-GRWFLAGVTSWG--HGCGRIGFPGVYMRATAVREWI----SIHLP 787

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	74/248 (30%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060
		Tryp_SPc	232..462	CDD:238113
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113	75/252 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010