DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and zgc:154142

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001092710.1	Gene:	zgc:154142 / 555481	ZFINID:	ZDB-GENE-070615-2	Length:	1090	Species:	Danio rerio

Alignment Length:	300	Identity:	89/300 - (29%)
Similarity:	125/300 - (41%)	Gaps:	69/300 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 IGGRIAGGELARANQFPYQVGLSI---EEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLG 89
            :..||..||.|..:.:|:||.:.:   .||..:...||.:||...::||||||..:      |..
Zfish   583 VNTRIVNGEPANPHSWPWQVSMQVLRDSEPPMLGHTCGGTLIHKNWVLTAAHCFIR------YAD 641

  Fly    90 GVLR----LAPRQLIRSTNPE-------VHLHPDW---NCQSLENDIALVRLPEDALLCDSIRPI 140
            .:.|    |....|..|.:.|       ::.|..:   ...::|.|||||||..:....:.|...
Zfish   642 ELHRWKMCLGKHNLTVSESTEQCFNVLGIYRHEGFQYPTVPTVEFDIALVRLDGEVTATEHIDFA 706

  Fly   141 RLPG----LSSSRNSYDYVPAIASGWGRMNDESTA--ISDNLRYVYRFVESNEDC---EYSYANI 196
            .||.    |...:..|      |:|||.....|||  :::.|..|...|...|.|   :|.:..:
Zfish   707 CLPSFEELLPGGKKCY------ATGWGDETGNSTAPKVAETLNQVALPVVPYETCKRMDYWWFQV 765

  Fly   197 KPTNICMDTTGG---KSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCT-KGYPSVFTRITA 257
            |.:.||...|..   ||.|.||||||||..|.......:.|:||:| ..||. ...||||||.:.
Zfish   766 KTSMICCGYTSPDELKSVCQGDSGGPLVCQDSPSAPWEVHGITSFG-PIGCVFDKKPSVFTRSSV 829

  Fly   258 YLDWI--------------------------GEVSGVHYP 271
            ||.||                          |.|:.:|:|
Zfish   830 YLPWIENVIRKDIYDFTTSGCGGLKDLFGTEGTVASMHHP 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	83/260 (32%)
zgc:154142	NP_001092710.1	CUB	57..159	CDD:238001
		CUB	172..280	CDD:238001
		CUB	310..420	CDD:238001
		CUB	432..546	CDD:238001
		Tryp_SPc	586..834	CDD:214473	83/260 (32%)
		Tryp_SPc	587..837	CDD:238113	84/262 (32%)
		CUB	850..959	CDD:238001	3/19 (16%)
		CUB	971..1080	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000