DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and C1s1

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	262	Identity:	80/262 - (30%)
Similarity:	117/262 - (44%)	Gaps:	53/262 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLGGVLRLA 95
            ||.||:.|:...||:||  ....|.     ...:||::.::|||||.:||......|:|
Mouse   443 RIFGGQPAKIENFPWQV--FFNHPR-----ASGALINEYWVLTAAHVLEKISDPLMYVG------ 494

  Fly    96 PRQLIRST---------NPEVHLHPDWNCQ-------SLENDIALVRLPEDALLCDSIRPIRLPG 144
             ...:|:|         :..|.:||.|..:       :.:||||||:|.:...:...:.||.|||
Mouse   495 -TMSVRTTLLENAQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDPVKMGPKVSPICLPG 558

  Fly   145 LSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEY---SYANIKPTN------ 200
            .||..|.......:.||||  :.|......|||.....|.|.|.|:.   ....::|.:
Mouse   559 TSSEYNVSPGDMGLISGWG--STEKKVFVINLRGAKVPVTSLETCKQVKEENPTVRPEDYVFTDN 621

  Fly   201 -ICMDTTGGKSTCTGDSGGPLVYSDPVQNADI----LIGVTSYGKKSGCTKGYPSVFTRITAYLD 260
             ||....|..| |.|||||...:..|  |..:    :.|:.|:||:.| |.|   |:|::..|:|
Mouse   622 MICAGEKGVDS-CHGDSGGAFAFQVP--NVTVPKFYVAGLVSWGKRCG-TYG---VYTKVKNYVD 679

  Fly   261 WI 262
            ||
Mouse   680 WI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	78/260 (30%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	78/260 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000