DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Prss53

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	68/280 - (24%)
Similarity:	106/280 - (37%)	Gaps:	82/280 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SCLDMGHGIGGRIAGGELARA-NQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVA 83
            ||:    ..|...:||..|.| :|:|:...|.    :.....||.:|:|:..:||||||
  Rat   331 SCV----ACGSLSSGGPQAGALSQWPWDARLK----HHGKLACGGALVSEVVVLTAAHC------ 381

  Fly    84 ITYYLGGVLRLAPRQLIR------STNPE-----------VHLHPDWNCQSLENDIALVRLPEDA 131
               ::|       ||.:.      ...||           .:.||:..     :|:|.:.|.:..
  Rat   382 ---FIG-------RQTLEEWSVGLGAGPEEWGLKQLILHGAYTHPEGG-----HDVAFLLLAQPV 431

  Fly   132 LLCDSIRPIRLPGLSSSRNSYDYVPAIASGW--------GRMNDESTAISDNLRYVYRFVESNED 188
            .|...:||:.|| .:..|     :|....||        |..:..:..::         |.....
  Rat   432 TLGPGLRPLCLP-YADHR-----LPDGEHGWVLGLTREAGINHPHTVPVT---------VLGPMA 481

  Fly   189 CEYSYA-------NIKPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKK-SGCT 245
            |...:|       .|.|..||....|....|.|.||.|||:.  ::....|.|:.|:|.. .|..
  Rat   482 CSRQHAASGSTGVPILPGMICTTVVGEPPHCEGLSGAPLVHE--IRGTWFLAGLHSFGDTCQGSA 544

  Fly   246 KGYPSVFTRITAYLDWIGEV 265
            |  |:||..::||.||:..:
  Rat   545 K--PAVFAALSAYEDWVSNL 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	64/264 (24%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	65/263 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010