DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and prss27

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	292	Identity:	88/292 - (30%)
Similarity:	133/292 - (45%)	Gaps:	59/292 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ILVFLLILVQGR---SISCLDMGHG-IGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLI 66
            :|..||:|..|.   :....|.|.. :..||.||:.|:..|:|:||...    |:...:||.:||
Frog     4 LLQALLLLTPGLLGITPGATDCGIPLVSSRIMGGQSAQEGQWPWQVSFR----NNGGHFCGGTLI 64

  Fly    67 SDRYLLTAAHCV---EKAVAITYYLGGVLRLAP--RQLI----RSTNPEVHLHPDWNCQSLENDI 122
            |.:|:::||||.   ..|.::|..||..:...|  .|:.    .:||     :|.:..:....||
Frog    65 SKQYVISAAHCFPSSSSASSVTAVLGAYMIDQPDGNQVAIPVQSATN-----YPSYVNEGDSGDI 124

  Fly   123 ALVRLPEDALLCDSIRPIRLP--------GLSSSRNSYDYVPAIASGWGRMNDESTAISD-NLRY 178
            :||:|.......:.|.|:.||        ||.          ...:|||.:..:.:.:|. .|:.
Frog   125 SLVQLASPVTFTNYILPVCLPADTVTFPTGLQ----------CWVTGWGNIASDVSLVSPMTLQE 179

  Fly   179 V-YRFVESNEDCEYSY----------ANIKPTNICMD-TTGGKSTCTGDSGGPLVYSDPVQNADI 231
            | ...:::|| |...|          .::....||.. ..|||.:|.||||||||.|...|  ..
Frog   180 VAVPLIDANE-CNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSSSGQ--WF 241

  Fly   232 LIGVTSYGKKSGCTKGY-PSVFTRITAYLDWI 262
            |.||.|:|:  ||.:.| |.|:|.:.:|.|||
Frog   242 LAGVVSFGE--GCGQAYRPGVYTLMPSYTDWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	79/261 (30%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	78/260 (30%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910