DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and AgaP_AGAP012502

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_001230484.2	Gene:	AgaP_AGAP012502 / 4578454	VectorBaseID:	AGAP012502	Length:	829	Species:	Anopheles gambiae

Alignment Length:	276	Identity:	73/276 - (26%)
Similarity:	106/276 - (38%)	Gaps:	73/276 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GELARANQFPYQVGLSIEEPNDMYCW-CGASLISDRYLLTAAHCVEKAVAITYYLGGVLRLAPRQ 98
            |..::..:|.....:...:|.....| ||.|||...::||||||.:....          |.|..
Mosquito    19 GNPSKPGEFSAIAAIGWTKPGGTVNWNCGGSLIWANFILTAAHCTKDRDT----------LLPPD 73

  Fly    99 LIR-----------------STNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLS 146
            :||                 .|...|..||.:|..|:..||||:.|.|...:...:.|..| .|.
Mosquito    74 IIRIGDLNLYDDREDALVQERTIIRVIRHPLYNTSSVFYDIALLMLNEKVNIYFEVMPTCL-WLD 137

  Fly   147 SSRNSYDYVP---AIASGWGR----MNDESTAISDNLRYVYRFVESNEDCEYSYANIKPT----- 199
                  |.:|   ..|:|||.    ....:..|...|:.:     :|:|||..|:.:...
Mosquito   138 ------DNIPFSKVEAAGWGTSGFGYGKTNILIKAELKLM-----ANKDCESYYSQVASVKNGLM 191

  Fly   200 --NIC-----MDTTGGKSTCTGDSGGP----LVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFT 253
              .:|     ||      ||.||||||    |::.|  .....|:||||:|  ..|....|.|:.
Mosquito   192 EHQLCAWDKVMD------TCPGDSGGPLQHKLIFGD--YKVPFLVGVTSFG--LSCGNSQPGVYV 246

  Fly   254 RITAYLDWIGEVSGVH 269
            :::.:..||.|....|
Mosquito   247 KVSKFGSWIVETLQQH 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	69/267 (26%)
AgaP_AGAP012502	XP_001230484.2	Tryp_SPc	19..258	CDD:238113	71/270 (26%)
		Tryp_SPc	19..255	CDD:214473	69/267 (26%)
		Tryp_SPc	325..>418	CDD:304450
		Trypsin	621..823	CDD:278516
		Tryp_SPc	629..826	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910