DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and AgaP_AGAP012269

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_001238284.2	Gene:	AgaP_AGAP012269 / 4577485	VectorBaseID:	AGAP012269	Length:	649	Species:	Anopheles gambiae

Alignment Length:	283	Identity:	67/283 - (23%)
Similarity:	117/283 - (41%)	Gaps:	37/283 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VFLLILVQG----------RSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCG 62
            |.|.::.|.          |.:..:.:.|       .|..|:...:|:...:...:.:.|...||
Mosquito    14 VLLCVVAQSLGPNRLTCGKRRVKTIHLVH-------NGIDAKPGHWPWHAAIFHRKGDQMDYACG 71

  Fly    63 ASLISDRYLLTAAHCV------EKAVAITYYLGGV-LRLAPRQLIRSTNPEVHLHPDWNCQSLEN 120
            .|:|.:..:|||||||      .....|:.:||.| |:.....:...|..|:.:||.:|.....|
Mosquito    72 GSIIDENTILTAAHCVFLVNGLLPVSRISVHLGRVHLKEVSEFVQEHTVQELIVHPGYNSSRFVN 136

  Fly   121 DIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVES 185
            ||||::|.....:.:.::|:.|..:..::...........|:|.  :|...:|:.|:.....|..
Mosquito   137 DIALIKLTGSITMSEFVQPVCLWTMDKNQELIVGKTGTLVGFGL--NEQDVVSEQLKQASIGVVD 199

  Fly   186 NEDC----EYSYAN-IKPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSY---GKKS 242
            ...|    ..|:|| :.....|.......|.|.|||||.|.::  |:....:.||.|:   .:::
Mosquito   200 ALTCIKSDRLSFANQLTAEMFCGGGQSNVSACNGDSGGGLFFN--VEGKWFVRGVVSFIPVRQRT 262

  Fly   243 G-CTKGYPSVFTRITAYLDWIGE 264
            | |.....:.:..:..||.||.:
Mosquito   263 GLCDPSKYTAYADVAKYLGWIDQ 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	60/246 (24%)
AgaP_AGAP012269	XP_001238284.2	Tryp_SPc	41..285	CDD:238113	63/254 (25%)
		Tryp_SPc	43..283	CDD:214473	60/243 (25%)
		Tryp_SPc	418..636	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910