DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and prss36

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001005710.1	Gene:	prss36 / 448231	XenbaseID:	XB-GENE-5892976	Length:	719	Species:	Xenopus tropicalis

Alignment Length:	291	Identity:	86/291 - (29%)
Similarity:	131/291 - (45%)	Gaps:	46/291 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQISTILVFLLILVQGRSISCLDMGHGIG-----GRIAGGELARANQFPYQVGLSIEEPNDMYCW 60
            |:::...:.||..|....:|........|     .||.||..||...:|:||.|.....:    .
Frog     1 MELTETFLLLLAFVSPTIVSTTPAPPSCGSPLVSSRIVGGTDAREGAWPWQVSLRYRGSH----I 61

  Fly    61 CGASLISDRYLLTAAHCVEKAVAITYY--LGGVLRLA---PRQLIRSTNPEVHLHPDWNCQSLEN 120
            ||.|:|..:::||||||...:.:.:.|  ..|..|||   |.::....: .:.:||.::..:...
Frog    62 CGGSVIGTQWILTAAHCFGNSQSPSDYEVRLGAYRLAETSPNEITAKVD-RIIMHPQYDELTYFG 125

  Fly   121 DIALVRLPEDALLCDSIRPIRLPGLSSSRNSY-DYVPAIASGWGRMNDESTAISDNLRYVYRFVE 184
            ||||:||.........|.|:.||   |:.||: |.:....:|||:     ||.:.||.:.....|
Frog   126 DIALIRLTSPIDYTAYILPVCLP---SASNSFTDGMECWVTGWGK-----TAFNVNLPFPGTLQE 182

  Fly   185 ------SNEDCEYSY---------ANIKPTN-ICMD-TTGGKSTCTGDSGGPLVYSDPVQNADIL 232
                  :...|:..|         :.|.|:: ||.. :.|||.:|.|||||.||..  :|.....
Frog   183 VMTPLINRTRCDQMYHIDSPVSASSEIIPSDQICSGYSDGGKDSCKGDSGGALVCK--IQRVWYQ 245

  Fly   233 IGVTSYGKKSGCT-KGYPSVFTRITAYLDWI 262
            ||:.|:|  .||. ...|.|:|.:.||..|:
Frog   246 IGIVSWG--DGCAIANRPGVYTLVPAYQSWL 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	79/254 (31%)
prss36	NP_001005710.1	Tryp_SPc	37..276	CDD:238113	79/255 (31%)
prss36	NP_001005710.1	Tryp_SPc	385..622	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010