Protein Alignment Jon74E and KLK1

DIOPT Version :9

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 84/281 - (29%)
• Similarity: 126/281 - (44%)
• Gaps: 53/281 - (18%)

  Fly     8 VFLLILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCW----CGASLISD 68
            ::.|:|....|:........|..||.||.....:..|:|..|        |.:    ||..|:..
Human     1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAAL--------YHFSTFQCGGILVHR 57

  Fly    69 RYLLTAAHCVEKAVAITYYLGGVLRLAPRQLIRSTNPE--VHL-----HPDWNCQSLEN------ 120
            :::||||||:..    .|.|.    |....|....|..  ||:     ||.:|...|||
Human    58 QWVLTAAHCISD----NYQLW----LGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQAD 114

  Fly   121 -----DIALVRLPEDA-LLCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYV 179
                 |:.|:||.|.| .:.|:::.:.||.......|    ..:|||||.:..|:.:..|:|:.|
Human   115 EDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGS----TCLASGWGSIEPENFSFPDDLQCV 175

  Fly   180 YRFVESNEDCEYSYANIKPTN--ICM-DTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKK 241
            ...:..|::|:.::.. |.|:  :|: ...|||.||.|||||||:..      .:|.||||:|..
Human   176 DLKILPNDECKKAHVQ-KVTDFMLCVGHLEGGKDTCVGDSGGPLMCD------GVLQGVTSWGYV 233

  Fly   242 SGCTKGYPSVFTRITAYLDWI 262
            ...|...|||..|:.:|:.||
Human   234 PCGTPNKPSVAVRVLSYVKWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	78/256 (30%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	79/257 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920