Protein Alignment Jon74E and PRSS41

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001382429.1
• Gene: PRSS41 / 360226
• HGNCID: 30715
• Length: 334
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 81/266 - (30%)
• Similarity: 118/266 - (44%)
• Gaps: 42/266 - (15%)

  Fly    25 GH-GIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYY- 87
            || .|...:|||..:...::|:|..|.:...:.    ||.||:|.|::|:||||.:|    .||
Human    63 GHREIHALVAGGVESARGRWPWQASLRLRRRHR----CGGSLLSRRWVLSAAHCFQK----HYYP 119

  Fly    88 ------LGGVL-RLAPRQL----IRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIR 141
                  ||.:. |..|..|    .|....::.::|| ....|.|||||:||.........|:||.
Human   120 SEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSVTYNAYIQPIC 183

  Fly   142 LPGLSSSRNSYDYVPAIASGWGRMNDESTAISD--NLRYVYRFVESNEDCEYSYANIKPTNICMD 204
            :.  ||:.|.........:|||.::...|.:..  |||.....:.:|..|.|.:......::..|
Human   184 IE--SSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWD 246

  Fly   205 T-------TGGKSTCTGDSGGPLVYSDPVQNADIL---IGVTSYGKKSGCTKGYPSVFTRITAYL 259
            :       .|...||.||||||||.     :.|.|   :|:.|:|...| ....|.|:|.|:.|.
Human   247 SMFCAGAEDGSVDTCKGDSGGPLVC-----DKDGLWYQVGIVSWGMDCG-QPNRPGVYTNISVYF 305

  Fly   260 DWIGEV 265
            .||..|
Human   306 HWIRRV 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	75/254 (30%)
PRSS41	NP_001382429.1	Tryp_SPc	71..311	CDD:238113	77/256 (30%)