Protein Alignment Jon74E and PRSS48

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 82/276 - (29%)
• Similarity: 126/276 - (45%)
• Gaps: 40/276 - (14%)

  Fly     5 TILVFLLILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDR 69
            |:|:.|.|.|.|:.:        ...|:.||:.|.|.::|:||.|..    |....||.||:|:|
Human     9 TLLLLLGISVCGQPV--------YSSRVVGGQDAAAGRWPWQVSLHF----DHNFICGGSLVSER 61

  Fly    70 YLLTAAHCVE---KAVAITYYLGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDA 131
            .:||||||::   ...:.|.:||.:.....|:.::....::.:||.:  |....|:||::|....
Human    62 LILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKY--QDTTADVALLKLSSQV 124

  Fly   132 LLCDSIRPIRLPGLSSSRNSYDYVPAI--ASGWGRMNDESTA-ISDNLRYVYRFVESNEDCEYSY 193
            ....:|.||.||.::...    .:|..  .:|||::.:.|.. ....|:.....:...:.||..|
Human   125 TFTSAILPICLPSVTKQL----AIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLY 185

  Fly   194 -----------ANIKPTNICM-DTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTK 246
                       ..||...||. ||...|.:|.|||||||  |..:....|..||.|:|.:  |.|
Human   186 NPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPL--SCHIDGVWIQTGVVSWGLE--CGK 246

  Fly   247 GYPSVFTRITAYLDWI 262
            ..|.|:|.:..|..||
Human   247 SLPGVYTNVIYYQKWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	74/248 (30%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	75/249 (30%)