Protein Alignment Jon74E and OVCH2

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: XP_047282834.1
• Gene: OVCH2 / 341277
• HGNCID: 29970
• Length: 569
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 81/299 - (27%)
• Similarity: 130/299 - (43%)
• Gaps: 73/299 - (24%)

  Fly    28 IGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCV--EKAVAITYYLGG 90
            |..||.||.......:|:||.|...:.:    .||.|::|.::::|||||:  ...|:......|
Human    52 IFSRILGGSQVEKGSYPWQVSLKQRQKH----ICGGSIVSPQWVITAAHCIANRNIVSTLNVTAG 112

  Fly    91 VLRLAPRQLIRSTNP--------EVHLHPDWNCQS-LENDIALVRLPEDALLCDSIRPIRLPGLS 146
            ...|:      .|:|        .|.:||.::.:. ::.||||:::.........:.||.||.|
Human   113 EYDLS------QTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPEL- 170

  Fly   147 SSRNSYD--YVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYANIK-----PTNICMD 204
              |..::  :: ...:||||:. |...:|..|:.|...:.:.|:|..:...:|     .|.:|..
Human   171 --REQFEAGFI-CTTAGWGRLT-EGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTG 231

  Fly   205 -TTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGY-----------PSVFTRITA 257
             ..||:..|.|||||.|:..:. :.|..|.||||:|  .||.:|:           |.:||.|:.
Human   232 FPDGGRDACQGDSGGSLMCRNK-KGAWTLAGVTSWG--LGCGRGWRNNVRKSDQGSPGIFTDISK 293

  Fly   258 YLDWIGE---------------------VSG----VHYP 271
            .|.||.|                     |||    :|:|
Human   294 VLPWIHEHIQTGNRRKSSRAWCSEQDVIVSGAEGKLHFP 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	72/260 (28%)
OVCH2	XP_047282834.1	Tryp_SPc	56..301	CDD:238113	73/262 (28%)
		CUB	320..424	CDD:238001	5/13 (38%)
		CUB	435..546	CDD:238001