DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and Prss53

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	290	Identity:	71/290 - (24%)
Similarity:	122/290 - (42%)	Gaps:	64/290 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ILVFLLILVQGRSI---SCLDMGHGIGGRIAGGELARANQFPYQV-----GLSIEEPNDMYCWCG 62
            ::|..:::::|...   :|...|.|......|..|  ..::|:|.     |:.|         |.
Mouse    10 LIVGAVVVIEGLQAAQRACGQRGPGPPEPQEGNTL--PGEWPWQASVRRQGVHI---------CS 63

  Fly    63 ASLISDRYLLTAAHCVEKAVAITYYLGGVLRLAPRQLIRSTNPE------VHLHPDWNCQSLEND 121
            .||::|.::||||||.||..........|:..:.:|..:|...|      :.|...:|..|..:|
Mouse    64 GSLVADTWVLTAAHCFEKMATAELSSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQGSD 128

  Fly   122 IALVRLPEDAL---LCDSIRPIRLPGLSSSRNSYDYVPAIASGWGRMNDESTA-ISDNLRYVYRF 182
            :||::|....:   ||       ||     :.:|.: |..||.|....|::|: :|..||.:...
Mouse   129 LALLQLTHPTVQTTLC-------LP-----QPTYHF-PFGASCWATGWDQNTSDVSRTLRNLRLR 180

  Fly   183 VESNEDCEYSYANI---------KPTNICMDT-TGGKSTCTGDSGGPLVYSDP----VQNADILI 233
            :.|...|...|..:         :|..:|... .|.:..|.||||||::..:|    ||     :
Mouse   181 LISRPTCNCLYNRLHQRLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQ-----V 240

  Fly   234 GVTSYGKKSGCT-KGYPSVFTRITAYLDWI 262
            |:.|:..|  |. :..|.:.|.:..:..|:
Mouse   241 GIISFTSK--CAQEDTPVLLTDMAVHSSWL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	65/260 (25%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		5/20 (25%)
		Tryp_SPc	45..271	CDD:238113	64/253 (25%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920