DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and AgaP_AGAP011914

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_552329.3	Gene:	AgaP_AGAP011914 / 3291452	VectorBaseID:	AGAP011914	Length:	398	Species:	Anopheles gambiae

Alignment Length:	266	Identity:	82/266 - (30%)
Similarity:	120/266 - (45%)	Gaps:	36/266 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHC-VEKAV 82
            ::| |.|......|..|.....|::|...||.....:.::  ||::::::|::|||||| :::..
Mosquito   146 LAC-DCGRHRTPTIVNGFPTLTNEYPMMAGLWDNSVSRVF--CGSTIVTNRHVLTAAHCLLDRTA 207

  Fly    83 AITYYLGG------------VLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCD 135
            |.|..|.|            .||:.....|:        ||.:|..|..||||||:..:..:...
Mosquito   208 AGTRVLVGEQNTNITNETPYTLRMLVSTFIK--------HPSYNPTSKANDIALVQTFDTIVFNP 264

  Fly   136 SIRPIRLP---GLSSSRNSYDYVPAIASGWGRMNDESTAISDNLRYVYRFVESNEDCEYSYA-NI 196
            .:..:.||   |.||..|:    ...|.|||.: |.....|..|......|.|:..|....: .|
Mosquito   265 GVGRVCLPFRFGTSSFENA----RLSALGWGAI-DFGAPSSKELLQTTLAVVSSTSCGTKLSRTI 324

  Fly   197 KPTNICMDTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDW 261
            ..:.:| ....|..||..||||||.|:||.......|||..:|  ..|...:|||.||:|:||||
Mosquito   325 LASQMC-TFAAGNDTCQNDSGGPLYYTDPNSQLVYSIGVVGFG--VACASSFPSVNTRVTSYLDW 386

  Fly   262 IGEVSG 267
            |...:|
Mosquito   387 ISSTTG 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	76/247 (31%)
AgaP_AGAP011914	XP_552329.3	CUB	34..143	CDD:238001
		Tryp_SPc	158..390	CDD:238113	78/249 (31%)
		Tryp_SPc	158..387	CDD:214473	76/246 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	2	1.910