DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon74E and plg

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	263	Identity:	80/263 - (30%)
Similarity:	122/263 - (46%)	Gaps:	68/263 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLGGVLRL 94
            |||.||.:::.:.:|:|:.|   .......:||.:||..::::|||||:|
Zfish   587 GRIVGGCVSKPHSWPWQISL---RTRGKIHFCGGTLIDPQWVVTAAHCLE--------------- 633

  Fly    95 APRQLIRSTNPEVH-----LHPDWNCQSLE--------------NDIALVRLPEDALLCDSIRPI 140
                  ||.:|..:     :|.:...:|.:              .||||::|...||:.|.:.|:
Zfish   634 ------RSDSPSAYKIMLGIHTERATESSKQERDVTKIIKGPAGTDIALLKLDRPALINDKVSPV 692

  Fly   141 RLPGLSSSRNSYDY-VPA----IASGWGRMNDESTAISDNLRYVYRFVESNEDCEY-SYAN--IK 197
            .||       ..|| ||:    ..:|||...|  |.....|:.....|..|:.|.. |:.|  :|
Zfish   693 CLP-------EKDYIVPSNTECYVTGWGETQD--TGGEGYLKETGFPVIENKVCNRPSFLNGRVK 748

  Fly   198 PTNICM-DTTGGKSTCTGDSGGPLV-YSDPVQNADILIGVTSYGKKSGCTKGY-PSVFTRITAYL 259
            ...:|. :..||..:|.|||||||| |:   ||..:|.||||:|  .||.... |.|:||::.::
Zfish   749 DHEMCAGNIEGGNDSCQGDSGGPLVCYA---QNTFVLQGVTSWG--LGCANAMKPGVYTRVSKFV 808

  Fly   260 DWI 262
            |||
Zfish   809 DWI 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	77/260 (30%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527
		Tryp_SPc	589..813	CDD:238113	78/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I4208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910