DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon74E and Tmprss11e

DIOPT Version :9

Sequence 1:	NP_001189126.2	Gene:	Jon74E / 39959	FlyBaseID:	FBgn0023197	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	XP_038948843.1	Gene:	Tmprss11e / 305265	RGDID:	1561698	Length:	444	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	78/253 - (30%)
Similarity:	118/253 - (46%)	Gaps:	35/253 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RIAGGELARANQFPYQVGLSIEEPNDMYCW-----CGASLISDRYLLTAAHCV---EKAVAITYY 87
            ||.||..|...::|:|..|.         |     |||:|||:.:|::||||.   :.....|..
  Rat   212 RIVGGTSAEEGEWPWQSSLQ---------WDGSHRCGATLISNTWLVSAAHCFRTHKDPSRWTAS 267

  Fly    88 LGGVLRLAPRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSY 152
            .|..|:  |.:|..... .:.:|..:|..|.:.|||||.|.......:::..:.||..     ::
  Rat   268 FGATLQ--PPKLTTGIR-RIIVHEKYNYPSHDYDIALVELSRPVPCTNAVHKVCLPDA-----NH 324

  Fly   153 DYVPA---IASGWGRMNDESTAISDNLRYVYRFVESNEDCE--YSY-ANIKPTNICMD-TTGGKS 210
            ::.|.   ..:|:|.:.::..| .:.||.|.......:.|.  .|| ..|.|..:|.. ..|.|.
  Rat   325 EFQPGQRMFVTGFGALRNDGFA-QNYLRQVQVDYIDTQTCNRPQSYNGAITPRMLCAGFLKGEKD 388

  Fly   211 TCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDWIGEVSGV 268
            .|.||||||||..| |::...|.||.|:|.:.| ....|.|:||:||:.|||...:|:
  Rat   389 ACQGDSGGPLVTPD-VRDVWYLAGVVSWGDECG-QPNKPGVYTRVTAFRDWITSNTGI 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	75/245 (31%)
Tmprss11e	XP_038948843.1	SEA	71..176	CDD:396113
Tmprss11e	XP_038948843.1	Tryp_SPc	213..441	CDD:238113	76/247 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010