Protein Alignment Jon74E and GZMB

DIOPT Version :10

• Sequence 1: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_004122.2
• Gene: GZMB / 3002
• HGNCID: 4709
• Length: 247
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 78/268 - (29%)
• Similarity: 122/268 - (45%)
• Gaps: 42/268 - (15%)

  Fly     6 ILVFLLILVQGRSISCLDMGHGIGGRIAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRY 70
            ||:.|..|:..|:.:         |.|.||..|:.:..||...|.|.:...:. .||..||.|.:
Human     4 ILLLLAFLLLPRADA---------GEIIGGHEAKPHSRPYMAYLMIWDQKSLK-RCGGFLIRDDF 58

  Fly    71 LLTAAHCVEKAVAITYYLGGVLRLAP-RQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLC 134
            :||||||...::.:|.....:....| :|.|....|..  ||.:|.::..|||.|::|...|...
Human    59 VLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIP--HPAYNPKNFSNDIMLLQLERKAKRT 121

  Fly   135 DSIRPIRLPGLSSSRNSYDYVP---AIASGWGRMNDESTA----ISDNLRYVYRFVESNEDCEYS 192
            .:::|:|||.     |.....|   ...:|||:     ||    .|..|:.|...|:.:..||..
Human   122 RAVQPLRLPS-----NKAQVKPGQTCSVAGWGQ-----TAPLGKHSHTLQEVKMTVQEDRKCESD 176

  Fly   193 YANIKPTNI--CM-DTTGGKSTCTGDSGGPLVYSDPVQNADILIGVTSYGKKSGCTKGYPSVFTR 254
            ..:...:.|  |: |....|::..||||||||.:...|      |:.|||:.:|..   |...|:
Human   177 LRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQ------GIVSYGRNNGMP---PRACTK 232

  Fly   255 ITAYLDWI 262
            :::::.||
Human   233 VSSFVHWI 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	70/241 (29%)
GZMB	NP_004122.2	Tryp_SPc	21..243	CDD:238113	72/242 (30%)